晚期前列腺癌患者26例骨痛的综合治疗  

Therapeutic results of bone pain in 24 cases of patients with advanced prostate cancer

作　　者：程东升[1] 何晓伟[1] 张永革[1] 张伟[1] 

机构地区：[1]解放军第一医院,甘肃兰州730030

出　　处：《西北国防医学杂志》2011年第5期358-360,共3页Medical Journal of National Defending Forces in Northwest China

摘　　要：目的:观察晚期前列腺癌患者骨痛的治疗效果。方法:回顾性分析2005-09～2010-09的26例晚期前列腺癌骨痛患者临床资料,所有患者均已在8～32个月前行双侧睾丸切除术及内分泌治疗。针对患者骨痛,采用联合化疗(8例)、局部放疗(6例)、同位素治疗(4例)和帕米膦酸二钠(8例)等综合治疗。结果:26例经随访3个月～5年,平均30个月。完全缓解和明显缓解21例,轻度缓解和无缓解5例,有效率81%。缓解期为3～15个月,平均8个月。结论:积极的综合治疗能缓解晚期前列腺癌患者骨痛的临床症状,提高其生活质量。Objective：To observe the therapeutic results of bone pain in patients with advanced prostate cancer. Methods ： From September 2005 to September 2010, the clinical data of 26 cases of bone pain with advanced prostate cancer were surveyed. All patients had undergone bilateral orchidectomy and endocrinal therapy 8 to 32 months ago, and all cases were treated with combination chemotherapy （8 cases） , isotopic （4 cases） or local radioactive therapy （6 cases） and pamidronate （8 cases）. Results： Twenty - six patients were followed up for 3 months to 5 years （ median 30 months）. The results showed complete remission （CR） and partial remission （PR） in 21 cases, micro - remission and no remission in 5 cases, total effective rate was 81%. The duration of remission was for 3 to 15 months （median 8 months）. Conclusion： Active combination therapy can palliate the bone pain in patients with advanced prostate cancer, and improve their life quality.

关 键 词：前列腺癌 骨痛 联合化疗 放疗 

分 类 号：R737.25[医药卫生—肿瘤]