特发性震颤的临床和电生理学特点  

Clinical and electrophysiological features of essential tremor

作　　者：黄东雅[1] 安荷娣[1] 余飞[1] Ojha Rajeev 堵翠[1] 刘榕[1] 

机构地区：[1]同济大学附属东方医院神经内科,上海200120

出　　处：《临床神经病学杂志》2011年第5期331-333,共3页Journal of Clinical Neurology

摘　　要：目的探讨特发性震颤(ET)的临床和电生理学特点。方法回顾性分析并比较33例ET患者(ET组)和30例生理性震颤患者(对照组)的震颤类型、程度、幅度和负重对其的影响,以总结ET的临床和电生理学特点。结果 ET组患者动作性震颤(KT)的震颤程度明显高于对照组,震颤幅度明显大于对照组(均P<0.01);而姿势性震颤(PT)的震颤程度和幅度与对照组差异无统计学意义。负重前后两组震颤幅度的改变不明显。ET组负重前后震颤频率分别为(5.20±0.37)Hz和(4.91±0.50)Hz,二者差异无统计学意义;对照组负重前后震颤频率分别为(9.39±0.63)Hz和(5.84±0.58)Hz,负重后震颤频率明显降低(P<0.01)。结论 ET包括PT和KT,其中KT在震颤程度和幅度上均占优势。ET的震颤频率稳定,受外界环境的影响较小。Objective To explore the clinical and electrophysiological features of essential tremor（ET）.Methods The type,degree and range of tremor and the influence of weight on tremor of 33 ET patients（ET group） and 30 physiological tremor patients（control group） were retrospective analyzed and compared.And the clinical and electrophysiological features of ET were summarized.Results The tremor degree of kinetic tremor（KT） in ET group was significantly higher than that in control group,and the tremor range was significantly larger（all P0.01）;while the differences of tremor degree and range of postural tremor（PT） between ET group and control group were not significant.There was no significant change of tremor range before and after weight.The tremor frequency of ET group before and after weight was（5.20±0.37）Hz and（4.91±0.50）Hz,respectively;and there was no significant difference between them.The tremor frequency of control group before and after weight was（9.39±0.63）Hz and（5.84±0.58）Hz,respectively;and the tremor frequency was significantly decreased after weight（P0.01）.Conclusions ET includes PT and KT,and in which KT take up the advantage in degree and range of tremor.The frequency of ET is stable,and seldom to be influenced by external circumstances.

关 键 词：特发性震颤 动作性震颤 姿势性震颤 小加速器记录仪 

分 类 号：R741[医药卫生—神经病学与精神病学]