原发性急性闭角型青光眼周边虹膜切除术前后眼前段相干光断层扫描参数的对比研究  被引量:10

Comparison of anterior segment changes before and after laser peripheral iridectomy by anterior segment optical coherence tomography in eyes with primary acute angle closure glaucoma

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作  者:李媚[1] 刘杏[1] 钟毅敏[1] 曾阳发[1] 孔湘云[1] 曹丹[1] 郭歆星[1] 

机构地区:[1]中山大学中山眼科中心眼科学国家重点实验室,广州510060

出  处:《中华眼科杂志》2011年第10期871-875,共5页Chinese Journal of Ophthalmology

基  金:基金项目:广东省科技计划项目(20088030301334);广东省医学科研课题(B2009085)

摘  要:目的观察原发性急性闭角型青光眼(PAACG)周边虹膜切除(SPI)术前后的眼前段相干光断层扫描(AS—OCT)参数改变。方法自身对照研究。连续性收集37例(37只眼)周边虹膜前粘连不超过5个钟点的PAACG发作期患者临床资料,进行回顾性自身对照研究。所有患者均于SPI术前及术后1个月行AS—OCT检查,检查项目包括中央前房深度、前房角开放距离、小梁网与虹膜间面积、前房角隐窝面积、前房宽度、前房容积及晶状体矢高。手术后与手术前检测参数比较,服从正态分布的采用配对t检验,不服从正态分布的采用配对秩和检验。结果37例(37只眼)PAACG患者SPI手术前的AS.OCT检测参数:距巩膜突750μm处,前房角开放距离(0.088±0.078)μm、小梁网与虹膜间面积(0.050±0.048)mm2、前房角隐窝面积(0.059±0.057)mm2、前房面积(12.332±2.457)mm2、前房容积(73.131±16.976)mm2;SPI术后AS—OCT检测参数:距巩膜突750μm处,前房角开放距离(0.125±0.072)μm、小梁网与虹膜间面积(0.091±0.041)Hmm2、前房角隐窝面积(0.095±0.042)mm2、前房面积(14.230±2.000)mm2、前房容积(90.074±16.796)mm2;SPI术后上述检测参数均高于术前,差异有统计学意义(t=-8.015~1.066,P=0.001~0.044)。但中央前房深度、前房宽度及晶状体矢高与术前相比无明显变化,差异无统计学意义(t=-1.505~0.516,P=0.102~0.609)。结论PAACG患者SPI术后可以解除瞳孔阻滞,使前房角开放距离、小梁网与虹膜间面积、前房角隐窝面积增宽,前房面积和容积增加,但前房深度和晶状体矢高不变。Objective To evaluate the changes of anterior segment configuration after surgical peripheral iridectomy (SPI)in patients with primary acute angle closure glaucoma (PAACG) by using anterior segment optical coherence tomography (AS-OCT). Methods This retrospective self control study consisted of thirty-seven eyes of 37 patients with PAACG who were consecutively recruited in Zhongshan Ophthalmic Center. The peripheral anterior synechiae (PAS) of these patients was less than 5 clock time point. Central anterior chamber depth (ACD), angle opening distance (AOD), trabecular iris area (TISA) , angle recess area (ARA), anterior chamber width (ACW) , anterior chamber volume (ACV), and crystalline lens rise (CLR) were measured using AS-OCT before and one month after SPI. Results After SPI, AOD (0. 125 ±0.072) μm, TISA (0.091 ±0.041) mm2, ARA (0.095 ±0.042) mm2, ACA ( 14. 230 ± 2. 000 ) mm2 and ACV ( 90. 074± 16. 796 )mm3 were significantly increased compared with before SPI AOD ( 0. 088 ± 0. 078 ) μm, TISA ( 0. 050 ± 0. 048 ) mm2, ARA ( 0. 059 ±0. 057 ) mm2, ACA ( 12. 332 ± 2. 457 )mm2, ACV (73. 131 ± 16. 976 ) mm3 ( t = - 8. 015 to 1. 066, P = 0. 001 to 0. 044 ), respectively. There were no significantly changes in ACD, ACW and CLR(t = - 1. 505 to 0. 516,P =0. 102 to 0. 609). Conclusions PAACG can be controlled by SP1 resulting in an increase of AOD, TISA, ARA,ACA and ACV, but not ACD or CLR.

关 键 词:眼前半段 体层摄影术 光学相干 虹膜切除术 青光眼 闭角型 前房 

分 类 号:R779.6[医药卫生—眼科]

 

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