氟桂利嗪联合手法复位治疗后半规管原发性良性阵发性位置性眩晕的临床疗效观察  

Flunarizine in combination with Epley maneuver in treating posterior semicircular canal benign paroxysmal positional vertigo

作　　者：张桂娟[1] 顾能荣[1] 何平[1] 钱晓琼[1] 

机构地区：[1]上海市长宁区中心医院耳鼻咽喉科,上海200336

出　　处：《中华耳科学杂志》2011年第3期312-314,共3页Chinese Journal of Otology

摘　　要：目的探讨氟桂利嗪联合手法复位治疗后半规管原发性良性阵发性位置性眩晕(posterior semicircular canal benign paroxysman positional vertigo,PC-BPPV)的治疗效果。方法对96例原发性PC-BPPV患者随机分为单纯手法治疗(Epley管石复位法)与联合氟桂利嗪进行治疗,观察治疗效果。结果经1次手法复位治疗后症状消失或明显减轻,一次治愈率两组基本相同。治疗4wk后,治疗组的治愈率为高于对照组(P<0.05)。随访3个月,共计有8例患者复发,总复发率为9.6%,其中治疗组为2.2%,对照组为18.4%。结论 Epley手法复位联合氟桂利嗪治疗PC-BPPV疗效显著,复发率低。Objective To evaluate the effectiveness of flunarizine combined with Epley maneuver in treating posterior semicircular canal benign paroxysmal positional vertigo （PC-BPPV）. Methods Ninety six patients diagnosed with PC-BPPV were randomly selected to receive either the Epley canalith repositioning maneuvers alone or in combination with flunarizine treatment. Results All patients experienced complete resolution or significant improvement of vertigo symptoms after a single repositioning treatment session, with an overall success rate of 71.88%. The overall success rate reached to 86.45% after 4 weeks 79.16% for Epley maneuver only and 93.75% for Epley maneuver combined with flunarizine.. Symptoms recurred in 8 patients during the 3 months follow-up period 18.42% for patients receiving Epley maneuver treatment alone and 2.22% for those receiving Epley maneuver combined with flunarizine. Conclusion Combining Epley maneuver with flunarize appears to improve treatment outcomes in PC-BPPV

关 键 词：位置性眩晕 半规管 耳石复位 氟桂利嗪 

分 类 号：R730.264[医药卫生—肿瘤] R651.11[医药卫生—临床医学]