Novel and Efficient One Pot Condensation Reactions between Ketones and Aromatic Alcohols in the Presence of CrO3 Producing α,β-Unsaturated Carbonyl Compounds  

作　　者：李亚男 陈道勇 

机构地区：[1]Department of Macromolecular Science, Fudan University, Shanghai 200433, China

出　　处：《Chinese Journal of Chemistry》2011年第10期2086-2090,共5页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （NSFC） （Nos. 50825303 and 30890140） and the Ministry of Science and Technology of China （No. 2009CB-930400）.

摘　　要：We report a new, effective and simple method for preparing a,fl-unsaturated carbonyl compounds by reacting ketones and aromatic alcohols at 56 ℃ in the presence of CrO3 （CrO3 acts as an oxidant and also a catalyst） for around 10 h. The condensation reactions occurred effectively among a wide combination of ketones and alcohols. The procedure is simple and the yields can be high up to 98%. And a probable mechanism is proposed.We report a new, effective and simple method for preparing a,fl-unsaturated carbonyl compounds by reacting ketones and aromatic alcohols at 56 ℃ in the presence of CrO3 （CrO3 acts as an oxidant and also a catalyst） for around 10 h. The condensation reactions occurred effectively among a wide combination of ketones and alcohols. The procedure is simple and the yields can be high up to 98%. And a probable mechanism is proposed.

关 键 词：one pot condensation reaction KETONE ALCOHOL CRO3 α β-unsaturated carbonyl compound 

分 类 号：O623.5[理学—有机化学] TQ174.1[理学—化学]