A Supramolecular Hydrogel Inspired by Elastin  

作　　者：丁磊 王淑芳 武文洁 胡月晗 杨翠红 谭鸣 孔德领 杨志谋 

机构地区：[1]Tianjin University of Science ＆ Technology, Tianjin 300457, China [2]Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China

出　　处：《Chinese Journal of Chemistry》2011年第10期2182-2186,共5页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （No. 31070856） and the Tianjin Technology Support Project （No. 07ZCKFSH03600）.

摘　　要：Self-assembly prevails in nature and learning from nature will lead to biofunctional materials. Inspired by the protein of elastin, we reported in this study on a supramolecular hydrogel beating the elastin repeating peptide of VPGAG. The visco-elasticity property, morphology of the nanostructures, and aromatic stacking in the self-assembled nanostructure were characterized by a rheometry, transmission electron microscope （TEM）, and fluorescence microscope, respectively. The biocompatibility of the gelator was also proved by an MTT assay. Though the supramolecular hydrogel failed to exhibit a high elasticity like elastin, the thixotropic hydrogel might have potentials for the applications in fields of cell culture, controlled-drug release, etc.Self-assembly prevails in nature and learning from nature will lead to biofunctional materials. Inspired by the protein of elastin, we reported in this study on a supramolecular hydrogel beating the elastin repeating peptide of VPGAG. The visco-elasticity property, morphology of the nanostructures, and aromatic stacking in the self-assembled nanostructure were characterized by a rheometry, transmission electron microscope （TEM）, and fluorescence microscope, respectively. The biocompatibility of the gelator was also proved by an MTT assay. Though the supramolecular hydrogel failed to exhibit a high elasticity like elastin, the thixotropic hydrogel might have potentials for the applications in fields of cell culture, controlled-drug release, etc.

关 键 词：SELF-ASSEMBLY HYDROGEL SUPRAMOLECULAR PEPTIDE 

分 类 号：TB383[一般工业技术—材料科学与工程] O648.17[理学—物理化学]