影响性生活的阴囊和包皮巨大良性间叶瘤1例报告  

Huge benign mesenchymoma with granulomatous inflammation in scrotum and penis： one case report

作　　者：于建红[1] 覃云凌[1] 肖敏勤[2] 江专新[1] 王晓东[1] 杨睿[1] 沈明[1] 

机构地区：[1]昆明医学院第二附属医院男性学科,昆明650101 [2]昆明医学院第二附属医院整形外科

出　　处：《中国男科学杂志》2011年第9期44-47,共4页Chinese Journal of Andrology

摘　　要：目的探讨阴囊和包皮巨大良性间叶瘤的临床病理特点及治疗方法。方法阴囊和包皮巨大良性间叶瘤1例，男，38岁，阴囊和包皮渐进性肿大1年余，不能性交3月余。B超提示：阴囊明显肿胀，最厚处1．4cm，于双侧睾丸下方可探及20cm×25cm×26cm大小的混合回声实质不均性肿块。CT报告：阴囊内巨大占位性病变，形态不规则，呈结节分叶状，无明包膜，密度均匀一致，其内见点状钙化，增强扫描后肿块呈现不均匀的斑片状强化。行肿块切除术，完整切除肿瘤。结果病理报告：表皮厚度大致正常，真皮层显著增厚，胶原纤维增生伴玻变；其内平滑肌、脂肪、神经组织均有纤维化和玻璃样变，另有散在慢性炎性细胞浸润和多核巨细胞反应；其中有较多的囊性空泡样结构形成，血管周围炎症细胞灶状浸润，以淋巴细胞为主，还有浆细胞、泡沫细胞、上皮样细胞和多核巨细胞。免疫组化结果：CD68（＋）。病理诊断：良性问叶瘤伴肉芽肿性炎。术后随访6个月未见肿瘤复发，且能完成正常性生活。结论阴囊和包皮巨大良性间叶瘤是少见的皮肤软组织良性肿瘤，确诊需依靠病理学检查，手术切除肿瘤为首选最佳治疗方法，本病预后良好，复发率较低。Objective To Investigate the clinical pathological features and treatment of huge benign mesenchymoma in scrotum and penis. Methods Size of scrotum and penis benign mesenchymoma of one case was 20cm × 25cm ×26cm. The photographic characters of the tumor included nodosity with lobular, no opparent envelope, uniformly dense, and punctate calcification. The mesenchymoma was resected completely. Results The pathologic characteristic showed that the smooth muscle, fat, nervous tissue all had fibrosis and hyalinization with scattered chronic inflammatory cell infiltration and multinucleated giant cell; which had more cystic vacuole-like structure formation, perivascular foci of inflammatory cells. Immunohistochemistry results was CD68 （＋）.No recurrence was found during a follow-up of 6 months. Conclusion Huge benign mesenchymoma in scrotum and penis was an infrequent neoplasm of soft tissue, which diagnosis depened on histopathological analysis and surgical resection was the first option for treatment of the tumor due to its low postoperative recurrence.

关 键 词：巨大良性间叶瘤 阴囊和包皮 临床研究 

分 类 号：R737.2[医药卫生—肿瘤]