局部进展期胃癌或结肠癌联合胰十二指肠切除术:附15例报告  

Enbloc pancreaticoduodenectomy for locally advanced gastric or colonic cancer: a report of 15 cases

作　　者：肖卫东[1] 李勇[1] 蔡军[1] 李学明[1] 揭志刚[1] 余永欢[1] 李太原[1] 

机构地区：[1]南昌大学第一附属医院普通外科,江西南昌330006

出　　处：《中国普通外科杂志》2011年第10期1091-1093,共3页China Journal of General Surgery

摘　　要：目的探讨局部进展期胃癌或结肠癌行胃癌或结肠癌切除联合胰十二指肠切除术的可行性及临床价值。方法回顾性分析2004年5月—2010年12月15例侵犯胰头十二指肠区域的局部进展期胃癌或结肠癌联合胰十二指肠切除术患者的临床资料,其中原发或复发胃癌12例,结肠癌3例。结果中位手术时间6 h(4～12 h),中位术后住院时间21 d(7～63 d)。并发症发生率为46.7%(7/15),再手术率为6.7%(1/15),病死率为6.7%(1/15)。中位生存期为23个月;1,2,3年累积生存率分别为62.2%,44.4%,22.2%。结论联合胰十二指肠切除术可作为局部进展期胃癌或结肠癌侵犯胰头十二指肠区域患者的治疗选择。该术式可延长部分患者的生存期。Objective To investigate the feasibility and efficacy of combination of gastric or colonic cancer resection with pancreaticoduodenectomy（en bloc PD） for locally advanced gastric or colonic cancer. Methods The clinical data of 15 patients with locally advanced gastric or colonic carcinoma with pancreatic head and duodenum involvement undergoing en bloc PD between May 2004 to December 2010 were retrospectively analyzed,and included 12 cases of primary or recurrent gastric cancer and 3 cases of colonic cancer. Results The median operating time was 6 h（4-12 h） and the median length of postoperative hospital stay was 21 d（7-63 d）.The incidence rate of complications was 46.7%（7/15）,reoperation rate was 6.7%（1/15） and mortality was 6.7%（1/15）.The median survival time was 23 months and the 1-,2-and 3-year cumulative survival rate was 62.2%,44.4% and 22.2%,respectively. Conclusions En bloc PD could be considered as one of the therapeutic options for locally advanced gastric or colonic cancer with pancreaticoduodenal involvement,and it may prolong the survival time of some these patients.

关 键 词：胃肿瘤/外科学 结肠肿瘤/外科学 胰十二指肠切除术 联合手术 

分 类 号：R735.23[医药卫生—肿瘤]