甲钴胺治疗大龄儿童弱视的疗效分析  

Study of methyeoba treatment in older children

作　　者：韩冰[1] 刘春民[1] 王媛[1] 陈静[1] 

机构地区：[1]暨南大学附属深圳眼科中心深圳市眼科医院,深圳518040

出　　处：《临床眼科杂志》2011年第5期444-446,共3页Journal of Clinical Ophthalmology

摘　　要：目的研究甲钴胺治疗大龄儿童弱视患者的疗效。方法 60例8～12岁屈光参差性弱视患者分为两组,对照组采用屈光矫正和遮盖治疗,药物组采用屈光矫正、遮盖和甲钴胺治疗。定期随访半年。对治疗前和治疗后的视力和图形视觉诱发电位(P-VEP)结果进行分析。结果治疗后药物组有效率为80.00%,对照组有效率为50.0%,两组间差异具有统计学意义(P<0.01)。治疗后与治疗前的P-VEP对比,潜伏期缩短,振幅增加,均具有统计学意义(对照组统计学处理P<0.05,药物组统计学处理P<0.01)。治疗后两组间P-VEP对比,差异具有统计学意义(P<0.01)。结论甲钴胺辅助治疗大龄弱视有较好的效果。Objective To investigate the treatment effect of Methyeoba for amblyopia in older children.Methods Totally 60 cases of anisometropic amblyopia children aged from 8 to 12 were divided into two groups,patients in the control group were treated with dioptric glass and eye shadow;patients in drug group received one more methyeoba treatment compared to control group.All patients were regular checked in following half year.Visual acuity,pattern-visual evoked potential（P-VEP） before and after treatment were tested and analyzed.Results After treatment,the effect rate for drug group was 80% and the control group was 50%,the difference between these two groups was significant on statistics.The comparison of the P-VEP before and after treatment was significant（on statistic calculation：P〈0.05 for control group and P〈0.01 for drug group）,the latency was reduced and the amplitude was increased.After treatment,the two groups difference of P-VEP was significant as well（P〈0.01）.Conclusion It is a good effective supported way for the amblyopia in older children to have Methyeoba treatment.

关 键 词：甲钴胺 弱视 综合疗法 

分 类 号：R777.44[医药卫生—眼科]