影响颞叶癫痫预后相关因素分析  

Related factors of prognosis for patients with temporal lobe epilepsy

作　　者：彭锋[1] 郑维红[1] 黄琼华[1] 

机构地区：[1]厦门大学附属中山医院神经内科,福建厦门361004

出　　处：《中华神经外科疾病研究杂志》2011年第5期436-438,共3页Chinese Journal of Neurosurgical Disease Research

基　　金：福建厦门市科技局基金资助项目(3502Z20084019)

摘　　要：目的研究颞叶癫痫患者病史、脑电图、头颅影像学资料等与其预后的关系。方法回顾分析我院确诊的99例颞叶癫痫患者病史、头颅影像学资料、发作间期脑电图资料、药物疗效,依据药物疗效分为难治性癫痫组46例,非难治性癫痫组53例,比较两组间差异。结果比较两组间差异发现:头颅MRI异常(χ2=7.55,P<0.01)、发作间期脑电图(electroencephalogram,EEG)反复异常(χ2=8.21,P<0.01)、初发年龄小(Z=-3.81,P<0.01)、病程长(Z=-4.41,P<0.01)与难治性颞叶癫痫有关。结论头颅MRI异常、发作间期EEG反复异常、初发年龄小、病程长为颞叶癫痫预后的不良因素。Objective To study the relationship between history,electroencephalogram（EEG）,neuroimaging and prognosis in patients with temporal lobe epilepsy（TLE）.Methods A total of 99 patients with TLE were analyzed retrospectively for the history,neuroimaging,interictal EEG and drug efficacy.All the cases were divided into retractory epilepsy group（46 cases） and non-retractory epilepsy group（53 cases） according to the drug efficacy and the difference between two groups were compared.Results There is a correlation between abnormal MRI（χ2=7.55,P0.01）,repeated interictal EEG abnormalities（χ2=8.21,P0.01）,seizure onset at early age（Z=-3.81,P0.01）,longer epilepsy duration（Z=-4.41,P0.01） and retractory epilepsy.Conclusion Abnormal MRI,repeated interictal EEG abnormalities,seizure onset at early age,and longer epilepsy duration are the risk factors for TLE.

关 键 词：颞叶癫痫 预后 癫痫 

分 类 号：R742.1[医药卫生—神经病学与精神病学]