了哥王脂溶性成分的气相色谱-质谱联用分析  

Analysis on the Liposoluble Constituent from Wikstroemia indica by Gas Chromatography-Mass Spectrometry

作　　者：刘明[1] 李玮[2] 徐丹[1] 周英[1] 

机构地区：[1]贵州大学生命科学学院,贵州贵阳550025 [2]贵阳中医学院,贵州贵阳550002

出　　处：《时珍国医国药》2011年第5期1102-1103,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家"十一五"科技支撑计划(No.2007BAI48B08-1)

摘　　要：目的研究瑞香科植物了哥王的脂溶性成分。方法用石油醚萃取了哥王的95%乙醇提取物,通过气相色谱-质谱联用技术(GC-MS)对其萃取物中的化学成分进行分离分析,并采用峰面积归一化法计算各成分相对百分含量。结果共分离鉴定出50种化合物,其中所鉴定成分占总流出峰面积的85.3%。结论为进一步研究哥王的毒性提供了实验数据及理论依据。Objective To study the liposoluble constituents from daphne plant Wikstroemia indica.Methods The 95% ethanol extract from Wikstroemia indica was obtained by petroleum ether,then was analyzed by gas chromatography-mass spectrometry（GC-MS）,and peak area normalization method was used to calculate the relative contents of each component.Results A total of 50 kinds of compounds were identified.The identified constituents represented 85.3% of total mass of the essential extraction.Conclusion The results provided experimental data and theoretical basis for further study of Wikstroemia toxicity.

关 键 词：了哥王 脂溶性成分 气相色谱-质谱 

分 类 号：R284.1[医药卫生—中药学]