原发性体液免疫缺陷病基因的分子生物学研究进展  

Study Progress of Molecular Biology of Genes Associated with Primary Humoral Immunodeficiency Disease

作　　者：陈启[1] 白丽[1] 

机构地区：[1]大理学院基础医学院医学微生物学及免疫学教研室,云南大理671000

出　　处：《实用儿科临床杂志》2011年第21期1675-1678,共4页Journal of Applied Clinical Pediatrics

基　　金：国家自然科学基金(30860262)

摘　　要：原发性体液免疫缺陷病是原发性免疫缺陷病中常见的一类疾病,其并发症严重威胁患儿健康。近年来,原发性体液免疫缺陷病逐渐受到医学界的重视,对原发性体液免疫缺陷病的研究取得了一些重要进展,特别是遗传学及分子生物学方面。研究原发性体液免疫缺陷病的基因情况,对指导临床的诊断、治疗均有积极意义。Primary humoral immunodeficiency disease is a common kind of primary immunodeficiency disease with severe and fatal complication. Recently, emphasis was paid on these diseases and many important results especially on the genetics causes of humoral immunodeficiency disease were obtained. Researches on genes associated with primary humoral immunodeficiency disease may provide potential strategy and helpful for the clinical diagnosis and treatment.

关 键 词：原发性体液免疫缺陷病 抗体 基因 突变 

分 类 号：R725.9[医药卫生—儿科]