全身弥散加权成像与同位素骨扫描诊断乳腺癌骨转移对比研究  

Comparison of the clinic value of whole body MR diffusion weighted imaging and radionuclide bone scan in the diagnosis of skeletal metastasis of breast cancer

作　　者：林建华[1] 谭理连[1] 何伟红[1] 黄勇[1] 李敏红[1] 邬恒夫[1] 

机构地区：[1]广州医学院第二附属医院放射科,广州510260

出　　处：《放射学实践》2011年第10期1107-1109,共3页Radiologic Practice

摘　　要：目的:比较全身弥散加权成像(WB-DWI)、同位素骨扫描(radionuclide bone scan)技术在乳腺癌骨转移的应用价值。方法:40例经病理证实为乳腺癌的患者分别作WB-DWI及同位素骨扫描检查。WB-DWI检查使用反转恢复平面回波弥散序列行全身扫描,将骨骼系统分为3个区域,分别记录每个患者各区域WB-DWI阳性病例数。对所有WB-DWI及同位素骨扫描影像表现的乳腺癌转移例数及发生部位行统计学比较。结果:WB-DWI阳性病例为35例,共检出病灶数为146个;同位素骨扫描阳性病例为30例,共检出病灶数为141个,WB-DWI的病灶检出率高于同位素骨扫描;WB-DWI与同位素骨扫描诊断乳腺癌骨转移例数及发生部位无统计学差异。结论:WB-DWI检查无辐射,覆盖范围大,具有较高的敏感性,对乳腺癌骨转移早期筛查、诊断及预后评价方面具有重要的临床应用价值。Objective：To compare the value of MR whole body diffusion weighted imaging （WB-DWI） and radionu- clide bone scan （RN） in the detection of bone metastasis of breast cancer. Methods： Forty patients with pathology proved breast cancer were enrolled. All patients underwent MR WB^DWI and RN,inversion recovery echo-planar diffusion scan se quence from head to foot was used for WIgDWI. The skeletal system was divided into three regions and the positive cases were recorded patient by patient in each region. Chi-square test was performed in patients and regions of bone metastasis de tected by WB-DWI and RN for comparison. Results： A total of 146 metastasis lesions in 35 patients were detected by Wig DWI while 141 lesions in 30 patients by RN. The detection rate of WB-DWI was higher than that of P-N. No statistic differ- ences were assessed in the number and locations of the bone metastasis diagnosed by WB-DWI and RN. Conclusion： MR Wig DWI has no radiation,large coverage and high sensitivity, which plays a significant role in early bone metastasis screening, diagnosis and prognosis evaluation of breast cancer.

关 键 词：磁共振成像 乳腺肿瘤 肿瘤转移 对比研究 

分 类 号：R737.9[医药卫生—肿瘤]