肠出血性大肠埃希菌感染的流行病学及临床诊治新进展  

Progress of epidemiology and dinical trealment on enterohaenmlyfic Escherichia coli

作　　者：胡沛[1] 赵刚德[1] 谢青[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院感染科,200025

出　　处：《国际流行病学传染病学杂志》2011年第5期341-344,共4页International Journal of Epidemiology and Infectious Disease

摘　　要：肠出血性大肠埃希菌（EnEC）是一种高度危险的致病菌，主要引起出血性肠炎，但有少部分患者感染后可能发展为威胁生命的疾病，例如溶血尿毒症综合征（HUs），而HUS是欧美儿童急性肾功能衰竭最常见的原因。绝大多数EHEC感染是可以预防的，一旦EHEC感染发生，目前还没有任何有效的措施预防HUS的发生。此文主要介绍了EHEC流行病学、临床诊治的研究进展，以及EHEC的暴发流行带来的经济损失，凸显了积极预防、早期诊断、及早干预的重要价值。Enterohaemolytic Escherichia coli（EHEC）is a serious cause of bloody diarrhoea. This bacteria is notable because of a few number of infected people develop the haemolytic uraemic syndrome, which is the most frequently cause of acute renal failure in children in the US and Europe. Most of the EHEC infection could be prevented, which is especially important because once an infection has been assured, no therapeutic interventions are available to reduce the risk of developing the haemolytic uraemic syndrome. In this article, the epidemiology of EHEC, the diagnosis and management of infection and their complications, the repercussions of infection including costs, and prevention are reviewed.

关 键 词：大肠杆菌O157 溶血尿毒症综合征 流行病学 诊断 治疗 

分 类 号：R515[医药卫生—内科学]