美沙酮维持治疗者脱失的影响因素单中心调查分析  

Influencing factors for dropout of patients on methadone maintenance treatment:a single center analysis

作　　者：黄乐萍[1] 赵敏[2] 刘人申[1] 史泊海[1] 袁伟君[1] 

机构地区：[1]上海市虹口区精神卫生中心,上海200083 [2]上海市精神卫生中心,上海200030

出　　处：《第二军医大学学报》2011年第10期1118-1121,共4页Academic Journal of Second Military Medical University

基　　金：上海市国际科技合作基金项目(09410707000);上海市虹口区卫生局科研基金(0902-11)~~

摘　　要：目的分析单中心美沙酮维持治疗者脱失的资料,探讨治疗脱失相关影响因素。方法样本来源于上海市虹口区精神卫生中心美沙酮维持治疗门诊的海洛因依赖者。研究组(n=54)为服药时间不足3个月退出治疗者,对照组(n=107)为服药时间超过6个月仍在维持治疗者。调查两组研究对象的社会人口学特征、成瘾程度、戒毒治疗、应对方式、社会支持等情况,分析各种潜在因素对海洛因依赖患者美沙酮维持治疗依从性的影响。结果对维持治疗的认识缺乏、低积极应对水平、高消极应对水平、社会支持差是影响美沙酮维持治疗脱失的危险因素。结论应针对危险因素实施综合干预,降低美沙酮维持患者的脱失率。Objective To investigate the associated factors influencing the compliance to methadone maintenance treatment by analyzing the data of dropout patients in a single center.Methods The subjects were heroin addicts from Shanghai Hongkou District Mental Health Center who were on methadone maintenance treatment（MMT）;they were divided into two groups：the study group（n=54）consisted of those who stopped methadone treatment within 3months,the control group（n= 107）were those who received treatment for more than 6 months.Factors such as social demographics,degree of drug dependence,methadone dose,coping style,and social support were collected,and their influences on dropout in methadone treatment were analyzed.Results Insufficient understanding,low positive response level,high negative response level,and social support were risk factors for the compliance to methadone maintenance treatment in heroin addicts.Conclusion Comprehensive interventions should be taken based on the risk factors,so as to reduce drop-out rate of MMT

关 键 词：海洛因依赖 美沙酮 维持治疗 脱失 

分 类 号：R749.611[医药卫生—神经病学与精神病学]