亚氯酸盐对三代大鼠的胚胎毒性  

Embryo toxicity of sodium chlorite on three generation rats

作　　者：吴明松[1] 李绍峰[2] 李百祥[3] 张玉玲[1] 黄君礼[1] 田禹[1] 

机构地区：[1]哈尔滨工业大学城市水资源与水环境国家重点实验室,黑龙江哈尔滨150090 [2]深圳职业技术学院建筑与环境工程学院,广东深圳518055 [3]哈尔滨医科大学公共卫生学院,黑龙江哈尔滨150006

出　　处：《中国环境科学》2011年第11期1900-1903,共4页China Environmental Science

基　　金：国家"863"项目(2006AA06Z309)

摘　　要：通过三代染毒实验,研究了亚氯酸盐对Wistar大鼠的长期胚胎毒性.结果表明:亚氯酸盐对胎鼠的内脏、骨骼发育无影响,没有表现出致畸作用,但长期摄入120,360mg/L亚氯酸盐可导致胎鼠体重减轻.亚氯酸盐对胎鼠的无明显副作用剂量为30mg/L,由实验结果可推算饮用水中亚氯酸盐最大污染水平目标值推算为1.1mg/L.The embryo toxicity of chlorite on Wistar rat was investigated through a three-generation test. No teratogenic effect, abnormal viscera and skeleton was observed on fetal rats. Exposure to 120 and 360mg/L chlorite for long term led to decreased body weights for the pups. No observed adverse effect level of chlorite on fetal rat was determined at 30mg/L, and the maximum contaminant level goal of chlorite in drinking water could be deduced as 1.1mg/L.

关 键 词：二氧化氯 消毒 亚氯酸盐 毒性 

分 类 号：X171.5[环境科学与工程—环境科学]