云南省慢性胰腺炎430例  

Etiology of chronic pancreatitis: an analysis of 430 cases in Yunnan Province

作　　者：耿琼梅[1] 张海蓉[1] 段丽平[1] 

机构地区：[1]昆明医学院第一附属医院消化内科,云南省昆明市650032

出　　处：《世界华人消化杂志》2011年第27期2886-2889,共4页World Chinese Journal of Digestology

基　　金：昆明医学院研究生创新基金资助项目;No.2011N06~~

摘　　要：目的:研究云南省慢性胰腺炎(chronic pancreatitis,CP)的病因.方法:回顾性分析云南省6所省市级综合医院(2003-01-01/2010-12-31)8年间确诊为CP的430例患者的病因构成及其随时间的变化,以及性别间的差异.结果:430例CP患者的病因中,胆系疾病占37.2%,酒精占42.1%,胰石症占29.5%,急性胰腺炎占22.8%,腹部手术史者占30.2%,多因素致病者占66.0%.前4年与后4年CP患者之比为1:1.59,其中患胆系疾病和饮精者分别占39.8%、36.1%;35.6%、45.8%.男女之比为2.9:1,男性患者以酒精为主,占56.3%;女性患者以胆道疾病为主,占32.7%.结论:我省CP的病因中以胆系疾病和酒精因素为主.近年来酒精已取代胆道疾病成为CP的第一致病因素.胰石症、急性胰腺炎、腹部手术史所占比重亦大,半数以上患者由多因素共同致病.AIM： To investigate the etiology of chronic pancreatitis （CP） in Yunnan Province. METHODS： The clinical data for 430 patients with CP who were treated in six provincial and municipal general hospitals in Yunnan Province between January 1, 2003 and December 31 were retrospectively analyzed to analyze etiological factors for this disease. RESULTS： Of all patients, 37.2% suffered from biliary diseases, 42.1% were drinkers, 29.5% had pancreatic stone disease, 22.8% had acute pancreatitis, 30.2% had undergone abdominal surgery, and 66.0% had multiple etiological factors. The ratio of the number of patients with CP in the first four years to that in the second four years was 1 ： 1.59. The percentages of patientssuffering from biliary diseases and drinkers accounted for 39.8% and 36.1% in the first four years and 35.6% and 45.8% in the second four years. The male to female ratio was 2.9 ： 1. In male patients, alcohol is the main etiological factor （56.3%）, while in females, biliary disease is the main etiological factor （32.7%）. CONCLUSION： Biliary disease and alcohol factor are the main etiological factors for CP in Yunnan Province. In recent years, alcohol has replaced biliary disease to become the major etiological factor for CP.

关 键 词：云南省 慢性胰腺炎 病因学 

分 类 号：R576[医药卫生—消化系统]