70岁以上老年早期肺癌的手术方式及预后  

Surgical procedure and prognosis analysis for elderly stage ⅠNSCLC patients above 70 years old

作　　者：张毅[1] 李元博[1] 姚舒洋[1] 支修益[1] 董宗俊[1] 

机构地区：[1]首都医科大学宣武医院胸外科首都医科大学肺癌诊疗中心,100053

出　　处：《中华胸心血管外科杂志》2011年第10期601-603,610,共4页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：目的探讨70岁以上老年Ⅰ期肺癌患者的手术方式及对预后的影响。方法回顾性分析2003年1月至2011年1月间71例70岁以上的Ⅰ期非小细胞肺癌患者。男51例、女20例，年龄70～84岁，平均74岁。其中肺楔形切除和肺段切除术22例，肺叶切除术49例。随访2～81个月，平均30个月。结果肺楔形切除、肺段切除术组及肺叶切除术组术后并发症发生率分别为36．4％和46．9％。术后住院天数11．36天和12．24天。3年总生存率85．9％和78．8％；5年总生存率56．4％和56．9％，以上各组比较均差异无统计学意义。分期为影响预后的独立因素。结论老年I期肺癌患者，肺楔形切除或肺段切除术可获得与肺叶切除术相似的预后。Objective The purpose of this study is to evaluate Surgical Procedure and Prognosis for elderly stage Ⅰ NSCLC patients above 70 years old. Methods The patients who were stage Ⅰnon-small cell lung cancer from 2003 to 2007 were enrolled （ n = 71 ）. The median age was 74 years （ ranged from 70 to 84 years）. The median follow-up of patients was 30 months （ ranged from 2 to 81 months）. Results The percentages of postoperative complications after sublobar resection and lo- bectomy patients were 36.4% and 46.9%, respectively. The period in hospital were 11.36 days and 12.24 days. The 3 year survival was 85.9% for patients undergoing sublobar resection and 78.8% for lobectomy. The 5 year survival was 56.4% and 56.9% respectively. No significant difference was observed between two types of surgical procedure in the elderly. Staging is the independent factor of prognosis. Conclusion Lobectomy is still the main therapy method for elderly stage ⅠNSCLC patients. Especially, for those who can undergo radical resection. But sublobar resection also appears to be a viable surgical treatment for patients with cardiopulmonary physiologic impairment.

关 键 词：癌 非小细胞肺 老年 胸外科手术 生存率 

分 类 号：R734.2[医药卫生—肿瘤]