视觉诱发电位结合MRI在视神经脊髓炎早期诊断中的临床应用  

Clinical application of visual evoked potential combined with magnetic resonance imaging in the early diagnosis of neuromyelifis optica

作　　者：余旭明[1] 詹奕红[2] 庄雄杰[1] 吴小强[1] 

机构地区：[1]福建厦门大学附属第一医院放射科,361000 [2]福建厦门大学附属第一医院神经内科,361000

出　　处：《医学信息（下旬刊）》2011年第10期1-1,共1页Medical information

摘　　要：目的：探讨视觉诱发电位（visualevokedpotential，VEP）和磁共振成像（magneticresonanceimaging，Mra）在视神经脊髓炎（Neuromyelitisoptica。NMO）中的诊断价值。方法：分别对40例NMO患者和40名正常志愿者进行VEP和MRI检测。结果：NMO组VEP异常36例，P100的潜伏期为（119．78±7．65）ms，对照组P100的潜伏期为（97．89±5．63）ms，两组相比差异有显著统计学意义（P〈0．01）；NMO组波幅为（6．41±2．52）μV，对照组波幅为（6．36±2．54）μV，两组相比差并元统计学意义（P〉0．05）。结论：VEP结合MRI对NMO的早期诊断和判断病情进程具有一定的临床价值。OBJECTIVE： To probe into the diagnostic value of visual evoked potential （VEP） and magnetic resonance imaging （MRI） in the diagnosis of neuromyelitis optica （NMO）. METHODS ： 40 NMO patients and 40 healthy volunteers were given VEP and MR/detection respectively, RESULTS ： There were 36 abnormal VEPs in NMO group with the P100 latent period （ 119.78 ± 7.65 ） ms. While the P100 latent period was 97.89 ± 5.63 ms in control group （ the healthy volunteer group）, there were obvious statistical significance between the two groups （P 〈 0.01 ） . There was no statistical significance between NMO group with （6.41 ± 2.52）μV amplitude and the control group （the healthy volunteer group） with （6.36 ± 2.54） μV amplitude. CONCLUSION： VEP combined with MRI had certain clinical value in early diagnosing and determining disease process of NMO.

关 键 词：视觉诱发电位 视神经脊髓炎 磁共振成像 

分 类 号：R744.5[医药卫生—神经病学与精神病学]