手术联合放化疗治疗小细胞肺癌疗效分析  

作　　者：陈贵和[1] 杨崇毛[1] 李治[1] 

机构地区：[1]怀化市第一人民医院心胸外科,418000

出　　处：《健康必读（下）》2011年第11期90-90,共1页

摘　　要：目的：探讨手术联合放化疗在小细胞肺癌（SCLC）治疗中的意义。方法：回顾性分析48例SCLC患者，其中22例患者术前予以放化疗，术后再给予化疗。26例患者术后予以辅助化疗。结果：术前＋术后化疗者1、3术后生存率分别为86．36％和59．09％，术后化疗者分别为80．76％和50％，两组问差异均元统计学意义（P〉0．05）。在两组患者中，NO-1，N21年生存率无统计学差异（P〉0．05），而3年生存率，N2患者明显低于NO-1（P〈0．05）。结论：对于局限期SCLC患者，积极开展手术结合放化疗的综合治疗能提高患者的生存率。Objective：To analyse the efficacy of surgical treatment combined with chemotherapy and radiotherapy for small cell lung cancer. Methods ：48 patients with small cell lung cancer were included the study. Among them, 22 cases received radiotherapy and chemotherapy before surgery and chemotherapy after surgery, while the other 26 cases received adjuvant chemotherapy after surgery. The patients was fo/lowed up for 1,3 year survival rates. Results：The 1,3 year survival rates were 86. 36% and 59.09% in patients undergoing surgery combined with radiotherapy and chemotherapy, and those were 80, 76% and 50% in patients with adjuvant chemotherapy after surgery. No sig- ulllcant difference was found between the two groups （ P 〉 0. 05 ） . There were significant differences in lyear and 3year survival rates between the N 0 - 1 and N2 patients （ P 〈 0. 05 ） . Conclusion ： Surgical treatment combined with chemotherapy may increase the survival rate of NO - 1 limited - stage small eelllung cancer.

关 键 词：小细胞肺癌 手术 化疗 放疗 

分 类 号：R734[医药卫生—肿瘤]