肝功能衰竭患者医院感染的临床特点分析  

Clinical characteristic analysis of nosocomia infection in liver failure

作　　者：刘树人[1] 罗显荣[1] 张雁[1] 陈汉先[1] 李灼亮[1] 

机构地区：[1]中国人民解放军第458医院全军肝脏病中心,广州市510600

出　　处：《中华实用诊断与治疗杂志》2011年第11期1053-1055,共3页Journal of Chinese Practical Diagnosis and Therapy

基　　金：总后勤部卫生部重点项目(08BJZ07)

摘　　要：目的探讨肝功能衰竭患者医院感染的特点。方法回顾性分析137例肝功能衰竭患者医院感染率、常见感染部位和常见菌株及其构成,感染与肝功能的关系及其对预后的影响。结果 137例肝功能衰竭患者发生医院内感染79例,感染率57.7%;常见感染部位依次为腹腔(22.9%)、胆管系统(22.3%)和胃肠道(17.5%);常见致病菌为大肠埃希氏菌(23.8%)、肺炎克雷伯菌(16.7%)、洋葱伯克霍尔德菌(11.9%);感染者较非感染者血清总胆红素高、凝血酶原活动度低,病死率高(P<0.05)。结论肝功能衰竭患者医院感染率高,以腹腔和大肠埃希氏菌感染多见,与肝功能有关并影响其预后。Objective To investigate the clinical characteristics of the nosocomia infection in liver failure. Methods The clinical data of t37 patients were retrospectively analyzed including the nosocomia infection rate, infection distribution sites and the common pathogens. The relationships between infection and liver functions were evaluated. Results In 137 patients with liver failure, the nosocomia infection occurred in 79 cases （57.7%）. The infection mostly occurred in abdominal cavity （22.9%）, biliary system （22.3%） and intestinal tract （17.5%）, respectively. The first three most common bacteria were Escherichia coli （23. 8%）, Klebsiella pneumonia （16. 7%） and Burkholderia cepacia （11.90%）. The nosocomia infection was correlated with the evaluated bilirubin and prolonged prothrombin time activity （P〈0.05）, and high mortality （P〈0.05）, Conclusion In liver failure, the nosocomia infection rate is high, the infection mostly occurs in abdominal cavity, and the most common bacteria is Escherichia coli. The infection is correlated with the liver functions and affects the prognosis

关 键 词：肝功能衰竭 医院感染 临床特点 

分 类 号：R575.3[医药卫生—消化系统]