颈动脉斑块超声造影增强特征与脑梗死的关系  

Relationship between contrast enhanced ultrasound imaging of carotid plaques and brain infarction

作　　者：白志勇[1] 李敬府[1] 杨玉杰[1] 张华斌[1] 刘蕾[2] 李小刚[2] 贾建文[1] 

机构地区：[1]北京大学第三医院超声诊断科,北京100191 [2]北京大学第三医院神经内科,北京100191

出　　处：《中国医学影像技术》2011年第11期2194-2197,共4页Chinese Journal of Medical Imaging Technology

基　　金：教育部留学回国人员科研启动基金(19-850-600)

摘　　要：目的探讨颈动脉斑块CEUS增强特征与脑梗死之间的关系。方法以彩色多普勒超声观察136例患者有无颈动脉斑块。将颈动脉斑块CEUS增强特征分为3级:无增强(1级)、基底部增强(2级)和中心部增强(3级)。比较脑梗死和无脑梗死患者颈动脉斑块CEUS增强特征,随访观察各级增强颈动脉斑块患者中的新发脑梗死病例比例。结果近期脑梗死同侧颈动脉斑块出现2级、3级增强者分别占30.77%(16/52)和40.38%(21/52),陈旧性脑梗死为28.00%(21/75)和21.33%(16/75),无脑梗死患者为24.03%(31/129)和8.53%(11/129),三者比较差异有统计学意义(χ2=31.56,P<0.01)。随访发现,1、2、3级增强斑块,同侧大脑半球新发脑梗死比例分别为1.47%(2/136)、8.93%(5/56)和7.14%(3/42),差异有统计学意义(P<0.05)。结论颈动脉斑块CEUS增强特征与脑梗死关系密切。Objective To investigate the correlation of carotid plaques characteristics detected by contrast enhanced ultrasound （CEUS） with brain infarction. Methods Carotid atherosclerosis plaques of 136 patients were imaged witb CEUS. Contrast enhancement within plaques were categorized as absent （grade 1 ）, peripheral （grade 2） and extensive internal （grade 3）. The patients Were followed up for stroke occurrence. Results Recent brain infarction patients had higher degree of plaques enhancement which were 30.77% （16/52） in grade 2 and 40. 380/00 （21/52） in grade 3, while old brain infarction had 28. 00% （21/75） in grade 2 and 21.33% （16/75） in grade 3, respectively, and patients without brain infarclion bad 24. 03% （31/129） in grade 2 and 8. 630/00 （11/129） in grade 3 （2 =31.56, P〈0.01）. Stroke occurrence ratio was 8.93% （5/56） in patients with grade 2 enhancement plaques and 7.14% （3/42） in patients with grade 3 enhancement plaques, both higher than that of patients with no plaques enhancement （2/136, 1. 47%, P〈0. 05）. Conclusion Carotid plaques contrast enhancement have significant correlation with brain infarction.

关 键 词：超声检查 造影剂 颈动脉 粥样硬化 脑梗死 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]