一种预测人工晶状体植入术后前房深度的新方法  

A new method for predicting anterior chamber depth in intraocular lens implantation

作　　者：宋文晓[1] 卢广文[1] 刘致滨[1] 杨晶娟[1] 朱懿恒[1] 

机构地区：[1]南方医科大学生物医学工程系,广东广州510515

出　　处：《南方医科大学学报》2011年第11期1895-1899,共5页Journal of Southern Medical University

基　　金：广东省教育部产学研结合重点项目(2010A090200003)

摘　　要：目的提出一种以对比敏感度曲线(contrast sensitivity function,CSF)为术后屈光状态评价标准的预测术后前房深度(anterior chamber depth,ACD)的方法。方法建立个性化的人眼模型,以人工晶状体替换自然晶状体,利用ZEMAX软件实现光线跟踪的方法,模拟人工晶状体眼的光学系统,通过光学优化得出最佳MTF曲线,以计算CSF从而得出最佳对比敏感度(CS)曲线,根据曲线确定最佳的ACD值。利用10例无视网膜疾病的白内障患者眼球数据分别用Holladay、Hoffer Q、SRK/T和上述方法分别预测其术后前房深度值并进行分析比较。结果利用Bland-Altman图对结果进行一致性分析,由图得知所有的点均落在95%一致性界限范围内,三个公式与本文方法的差值的绝对值最大分别为0.73、0.65、0.68 mm,计算结果的均值分别为5.846、5.804、5.825 mm,在临床范围内认为这两种方法计算的结果具有较好的一致性,可以用该方法对术后ACD进行预测。结论光学法的应用将描述屈光状态的对比敏感度曲线与影响术后屈光状态的前房深度建立起一定的联系,使得医生能够更好的满足患者的屈光状态要求,改善患者的生活质量。Objective To propose a method for predicting the postoperative anterior chamber depth value（ACD） based on the evaluation standard of contrast sensitivity function（CSF）.Methods In a personalized eye model,the natural lens was replaced with an artificial lens,and the tracing method based on ZEMAX software was utilized to simulate the pseudophakic optical system.The best MTF curve was obtained through optical optimization to calculate the CSF and determine the best contrast sensitivity（CS） curve.The best ACD value was acquired according to the CSF curve. The data form 10 cataract cases without retinal diseases were obtained and the postoperative ACD value was predicted using Holladay,Hoffer Q,SRK/T and the proposed method.Results Consistency analysis of the results showed that all the ACD values predicated by the 4 methods fell in 95% consistency within the boundaries,and the differences in the largest absolute value between the 3 methods（Holladay,Hoffer Q,and SRK/T） and the proposed method were 0.73 mm,0.65 mm,and 0.68 mm,and the calculation results of the mean value were 5.846 mm,5.804 mm,and 5.825 mm.Clinically,the two methods were deemed to have good consistency.Conclusion The proposed method establishes a connection between the contrast sensitivity curve and ACD to allow better refraction adjustment for the patients.

关 键 词：个性化人眼模型 对比敏感度函数 前房深度 

分 类 号：R779.6[医药卫生—眼科]