甲状腺功能亢进症合并脑梗死的临床研究  

Clinical Observation of Hyperthyroidism Complicated with Cerebral Infarction

作　　者：谌剑飞 

机构地区：[1]广东省珠海市第二人民医院 [2]珠海市中西医结合医院

出　　处：《中西医结合心脑血管病杂志》2011年第11期1322-1323,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的探讨甲状腺功能亢进症(甲亢)合并脑梗死的临床发病特点。方法回顾分析30例甲亢脑梗死患者临床特点;甲状腺功能(FT3、FT4、超敏促甲状腺素),凝血功能:血小板聚集率(PAgT)、血纤维蛋白原(FG)、活化部分凝血酶时间(APTT)和凝血酶原时间(PT)等指标水平及心电图变化。结果甲亢脑卒中组甲状腺激素(FT3、FT4)、凝血指标(PAgT、FG、ETL)、入院时血糖水平均显著高于正常对照组(P<0.05);促甲状腺素及高密度脂蛋白显著低于对照组(P<0.05);心电图以心律失常及ST-T段改变为主。结论甲亢脑卒中患者与上述原因关系密切,其独立或多种危险因素的作用,可能是促使或导致脑梗死发生的重要原因。Objective To investigate clinical characteristics of hyperthyroidism with cerebral infarction.Methods Clinical characteristics,thyroid function[free triiodothyronine（FT3）,free thyroxine（FT4） and thyroid stimulating hormone（sTSH）],coagulation [platelet aggregation test（PAgT）,fibrinogen（FG）,external thrombosis length（ETL）,activated partial thromboplastin time（APTT）,prothrombin time（PT）] and electrocardiogram（ECG） in 30 patient（pts） with hyperthyroidism and cerebral infarction were studied by retrospective analysis.Results The levels of FT3 and FT4,PAgT,FG,ETL,and blood glucose in pts at admission were significantly higher than that in normal controls（P0.05）.The levels of sTSH and high density lipoprotein in pts were significantly lower than that in control group（P0.05）.Conclusion Pts with hyperthyroidism and cerebral infarction are closely related the levels of FT3 and FT4,PagT,FG,ETL,and blood glucose.

关 键 词：甲亢症 脑梗死 甲状腺激素 凝血功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R255.2[医药卫生—临床医学]