马钱子中毒引起癫痫发作患者的远期预后  

Long-term Prognosis of Patients with Epilepsy Caused by Strychons Poisoning

作　　者：彭晓燕[1] 肖争[1] 全凤英[1] 

机构地区：[1]重庆医科大学附属第一医院,重庆400016

出　　处：《中国中医急症》2011年第11期1796-1797,共2页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的观察马钱子中毒所致癫痫患者的远期预后及对其生活质量的影响,探索其防治规律。方法对误服马钱子中毒引起癫痫发作的患者在总结其临床规律后进行长时间定期随访,观察患者的生存、认知、情感活动的变化和疾病治疗谱。结果 5例中有2例在随访中死亡,存活者中1例有明显的认知障碍和忧郁,1例合并有非痫性发作多次导致误诊误治,1例在癫痫得到控制后脑电图上仍有明显的痫样放电;几乎均对目前所使用的抗癫痫药物都存在不同程度的耐药。结论马钱子所致癫痫是一种耐药性癫痫,癫痫发作对患者的生活质量有明显的影响。Objective： To understand the long-term prognosis and quality of life of patients with epilepsy caused by strychnos poisoning,and to provide comprehensive information on the prevention and control of the sizures Methods： Some indices were observed in these patients including the cognition,the emotion activity changes and the disease treatment spectrum.Results： In the 5 patients with epilepsy caused by strychnine poisoning,2 people died in the follow-up.The survival of 1 significant cognitive impairment,and a depression.1 case of patients with non-epileptic seizures many times lead to misdiagnosis and mis treatment,one patient in the epilepsy under control.There are still significant the EEG epileptiform discharge.Meanwhile,there were different degrees of resistance in the currently used antiepileptic drugs.Conclusion： The epilepsy caued by strychnine poisoning is a drug-resistant epilepsy.Due to epileptic seizures,quality of life of patients has a significant impact.

关 键 词：癫痫 马钱子 耐药性 抗癫痫药 

分 类 号：R742.1[医药卫生—神经病学与精神病学]