微RNA与子宫内膜癌  

MiRNA and endometrial cancer

作　　者：梁静[1] 马本红[1] 张贵宇[1] 

机构地区：[1]山东大学齐鲁医院妇产科,济南250012

出　　处：《国际肿瘤学杂志》2011年第11期854-858,共5页Journal of International Oncology

基　　金：山东省科技攻关项目资助项目2008GG1000205

摘　　要：微RNA（miRNA）参与了肿瘤发生等多种生命活动，应用分子生物学与信息生物学方法探讨miRNA在肿瘤发生中所起的作用是目前研究的热点。近年来多种在子宫内膜癌中有特异研究价值的miRNA被发现，其作用机制也被深人探讨，这些结果为子宫内膜癌发病机制的研究提供了有效的依据。MicroRNA is a class of non-protein coding, single-stranded small RNAs of 22-25 nucleotides length. It takes part in many physiological processes including tumorigenesis. In the present focus studies, molecular biology and bioinformatics methods are used to study the role of miRNA in tumors. Several miRNAs with research value have been found and their mechanisms have been investigated in endometrial carcinoma.Results from the studis provide valid evidence for further research.

关 键 词：微RNAS 子宫内膜肿瘤 

分 类 号：R737.33[医药卫生—肿瘤]