复方苔藓散结合醋酸地塞米松贴膜治疗口腔糜烂型扁平苔藓临床疗效观察  

Treatment for erosive oral lichen planus with combined treatment of complex prescription of traditional Chinese medicine and dexamethasone acetate membrane

作　　者：刘巍[1] 杨京蓉[1] 于铁[2] 

机构地区：[1]大连大学附属中山医院口腔科,辽宁大连116001 [2]大连大学附属中山医院中医科,辽宁大连116001

出　　处：《中国实用口腔科杂志》2008年第12期728-729,共2页Chinese Journal of Practical Stomatology

摘　　要：目的探讨复方苔藓散结合醋酸地塞米松贴膜治疗口腔糜烂型扁平苔藓的临床疗效。方法将2003—2006年大连大学附属中山医院口腔科92例糜烂型扁平苔藓患者随机分为中药组31例,西药组30例及中西医结合治疗组31例。前两组分别采用复方苔藓散(中药)或地塞米松贴膜(西药)进行治疗,中西医结合组则采用二者结合进行治疗。于治疗结束时及治疗后1年内追踪疗效。结果停药后临床疗效的总有效率比较显示,与中药组(51.61%)相比,西药组(86.67%)及中西医结合组(80.65%)的差异均有统计学意义(P均<0.01);治疗后1年内追踪观察西药组有效病例总复发率(61.53%)明显高于其余两组(P<0.05)。结论中西医结合治疗口腔糜烂型扁平苔藓短期及长期观察均可取得良好疗效。Objective To study the treatment of erosive oral lichen planus with combined treatment of complex prescrip-tion of traditional Chinese medicine and dexamethasone acetate membrane.Methods A total of 92 patients suffered from erosive OLP were divided into 3 groups randomly:combined medicine group(n=31),Chinese medicine group(n=31)and western medicine group(n=30).The cases of combined medicine group were treated by complex prescription of traditional Chinese medicine and dexamethasone acetate membrane.And the other groups use only Chinese medicine or western medicine.The therapeutic effect was evaluated and analyzed statistically.Results At the end of treatment,the effective rates of 3 groups were 81%,51.61%and 86.67%(P<0.01).After 1 year,the recurrence rates of 3 groups were18.75%,61.53%and 20%respectively(P<0.01).Conclusion The therapy of integrated Chinese and western medi-cine has good short-term and long-term effect on erosive OLP.

关 键 词：糜烂型扁平苔藓 中草药 

分 类 号：R781.5[医药卫生—口腔医学]