Plasma hemoglobin concentration was related to estimated glomerular filtration rate in elderly patients with ischemic cardiomyopathy  

作　　者：Gang Li,~1 Zhihua Wang,~1 Canjing Zhang,~2 Yang Wang~1 1 Division of Cardiology, Department of Geriatrics, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China 2 Department of Function Examination, Chongqing Xijiao Hospital, Chongqing 400050, China 

出　　处：《Journal of Geriatric Cardiology》2008年第3期150-154,共5页老年心脏病学杂志（英文版）

基　　金：the Medical Science & Technology Research fund of Health Bureau of Chongqing City,China [No.2004(53)04-2-154];the Nature Science Research fund of Chongqing Science & Technology Com-mission of Chongqing City,China (No.CSTC,2007BB5276).

摘　　要：Objectives To study the relationship between plasma hemoglobin concentration and estimated glomerular filtration rate （eGFR） in elderly patients with ischemic cardiomyopathy （ICM）.Methods Clinical data of patients with coronary heart disease who were discharged from The First Affiliated Hospital,Chongqing Medical University between 2005 and 2007 were analyzed retrospectively. Echocardiography results,plasma hemoglobin and creatinine concentration were abstracted from the medical records.The study included 235 Chinese Hart patients with age 60 years and older with angiography confirmed coronary heart disease,silent myocardial ischemia or angina pectoris,of whom 154 had ICM defined as left ventricular end-diastolic diameter （LVDd）,male≥56 mm,female≥51 mm （63. 51±7.70 mm） measured by M-mode echocardiography.The differences in plasma hemoglobin concentration were analyzed retrospec- tively between patients with and without ICM,and between patients with an eGFR【60 ml·min^-1·1.73m^-2 and those with an eGFR≥60 ml·min^-1·1.73m^-2.Results There were no significant differences in plasma hemoglobin concentration and eGFR between ICM and non-ICM group (118.49±20.52 g·L^-1 vs.115.80±23.32 g·L^-1 and 75.13±24.21 ml·min^-1·1.73m^-2 vs.79.09±28.41 ml·min^{- 1}·1.73m^-2,respectively,both P】0.05).However,in both ICM and non-ICM groups,plasma hemoglobin concentration was lower in those with an eGFR【60 ml·min^-1·1.73m^-2 compared with compared with those with an eGFR≥60 ml·min^-1·1.73m^-2 group (112. 29±18.61 g·L^-1 vs.119.92±20.74L^-1,P【0.05);plasma hemoglobin concentration was related positively to eGFR.Conclusions There were no significant changes in plasma hemoglobin concentration and eGFR;however,plasma hemoglobin concentration was related to eGFR significantly positively in elderly patients with ICM due to coronaryObjectlves To stuaythe relationship between plasma hemoglobin concentration and estimated glomerular filtration rate (eGFR)in elderly patients with ischemic cardiomyopathy (ICM).Methods Clinical data of patients with coronary heart disease who weredischarged from The First Affiliated Hospital,Chongqing Medicai University between 2005 and 2007 were analyzed retrospectively.Echocardiography resuIts.plasma hemoglobin and creatinine concentration were abstracted from the medical records.The study included235 Chinese Han patients with age 60 years and older with angiography confwmed coronary heart disease.silent myocardial ischemia orangina pectoris,of whom 154 had ICM defined as left ventricular end-diastolic diameter(LVDd),male≥56mm,female≥51 mm(63.51±7.70 mm)measured by M-mode echocardiography.The differences in plasma hemoglobin concentration were analyzed retrospec-were no significant changes in plasma hemoglobin concentration and eGFR;however,plasma hernoglobin concentration was related toeGFR significantly positively in elderly patients with ICM due to coronary heart disease.

关 键 词：ischemic CARDIOMYOPATHY coronary heart disease SILENT myocardial ischemia ANGINA PECTORIS estimated glomerular filtration rate PLASMA HEMOGLOBIN concentration 

分 类 号：R541.6[医药卫生—心血管疾病]