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机构地区:[1]中山大学肿瘤防治中心放疗科,华南肿瘤学国家重点实验室,广东广州510060 [2]四川泸州医学院附属医院肿瘤科,四川成都646000
出 处:《中国神经肿瘤杂志》2008年第4期249-252,共4页Chinese Journal of Neuro-Oncology
摘 要:放射治疗为鼻咽癌首选治疗手段。近年来由于疗效不断得到改进,长期生存者的生存质量越来越多受到关注,放射性脑损伤是影响生存质量的重要并发症之一。本文对近年来国内外文献进行综合分析,介绍鼻咽癌放射性脑损伤的临床表现、现代影像学诊断、影响因素、发病机制和对生存质量的影响。Radiotherapy is the mainstay treatment for nasopharyngeal carcinoma. With the improvement of prognosis of patient with nasopharyngeal carcinoma, more attentions were paid to the long-term quality of life of patients with nasopharyngeal carcinoma. Radiation encephalopathy is a severe sequel, which significantly influences the quality of life. In this article, we reviewed the literatures and introduced clinical aspects of the post-radiation brain injure in patients with nasopharyngeal carcinomas, including manifestations, influencing factors, pathogenesis and quality of life.
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