Chemopreventive effect of oltipraz on AFB_1-induced hepatocarcinogenesis in tree shrew model  

作　　者：TW Kensler BD Roebuck 

机构地区：[1]Department of Environmental Health Sciences,Johns Hopkins School of Hygiene and Public Health,Baltimore.MD 21205,USA [2]Department of Pharmacology and Toxicology,Dartmouth Medical Schnool,Hanover,NH 03755,USA

出　　处：《World Journal of Gastroenterology》2000年第5期647-650,共4页世界胃肠病学杂志（英文版）

基　　金：USPHS grant CA-39416.

摘　　要：INTRODUCTIONHepatocellular carcinoma (HCC) is one of themajor cancers in the world with a mortality of morethan 250 000 cases yearly.More than 137 000 casesof HCC were diagnosed each year in China,whichacount approximately for more than 40 percent ofthe total number in the world.HCC has become thesecond major cause of death for cancer in

关 键 词：hepatocellular carcinoma tupajidae AFLATOXIN B1 hepatitis B virus incidence CARCINOGENS environmental 

分 类 号：R735.7[医药卫生—肿瘤]