子宫颈小细胞癌——一种特殊类型宫颈癌  

Small cell carcinoma of the cervix: A special type of cervical carcinoma

作　　者：张国楠[1] 徐世强[1] 姚宇琪[2] 谢瑞梦[1] 石宇[1] 宋水勤[1] 余健[1] 陈毅男[1] 

机构地区：[1]四川省肿瘤医院妇瘤科,成都610041 [2]四川省肿瘤医院病理科,成都610041

出　　处：《中国妇产科临床杂志》2000年第1期37-38,53,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的 了解子宫颈小细胞癌(SCCC)的临床病理与生物学行为特征,探讨其治疗方法。方法回顾性分析6例SCCC患者的临床病理资料及随访记录。结果Ib期Ⅰ例、Ⅱa期2例、Ⅲb期3例。盆腔淋巴结转移2例,肝等器官转移4例,对6例患者采用手术+放疗+化疗或放疗+化疗的综合治疗,2例分别已存活30、20个月,另4例分别存活10、11、13、14个月后死亡。结论 子宫颈小细胞癌与肺小细胞癌的组织病理学和生物学行为特征相似,早期易发生盆腔淋巴结和远处转移,对化学治疗比较敏感。对早期患者应行广泛性子宫切除术+盆腔淋巴结清扫术,术后给予辅助性放疗和化疗;对晚期患者应采用放疗和化疗。Objective The clinical - pathologic feature, biological characteristics and therapy regimens of small cell carcinoma of the cervix (SCCC) were studied. Methods The data and results of follow up of 6 patients with SCCC were retrospectively analyzed. Results One case was stage Ⅰ b, two were Ⅱ a, and three were Ⅲ b. The metastasis to pelvic lymphonodus, lungs and livers were found in early stage of SCCC. Treatments to these patients were combined therapy, including surgery, chemotherapy, radiotherapy or radiotherapy and chemotherapy. Two cases were alive 30 months and 20 months respectively. The other four died in 10, 11, 13 and 14 months respectively. Conclusion The histo- pathologic features and biologic characteristic behavior were similar between SCCC and small cell carcinoma of lung. Early metastasis and sensitivity to chemotherapy were found for both of them. It is necessary to take radical hysterectomy + pelvic lymphadenectomy and followed by adjuvant radiotherapy and chemotherapy for patients in early stage; however radiotherapy + chemotherapy is useful for advanced stage. The aim of chemotherapy is preventive and also for distant metastasis.

关 键 词：宫颈肿瘤 小细胞癌 化学治疗 

分 类 号：R737.33[医药卫生—肿瘤]