伽玛刀治疗听神经瘤后的面神经功能和听力保护  

Preservation of hearing and facial nerve function after Gamma knife therapy for acoustic neurinomas

作　　者：马志明 仇斌 唐建兵 侯永宏 马建荣 刘运生 

出　　处：《中南大学学报（医学版）》1999年第1期62-64,共3页Journal of Central South University ：Medical Science

摘　　要：以ＭＲ或ＣＴ为复查手段，随访经伽玛刀治疗的２１例听神经瘤病人，随访时间４～２５个月，平均１３个月。１年后肿瘤生长控制率为９５％，肿瘤缩小率为４３％，听力保存率为３６％。治疗后新的面神经病变发生率为２３３％，新的三叉神经病变发生率４８％。资料表明，伽玛刀治疗听神经瘤是一种安全有效的方法。Thirty five patients with acoustic neurinomas were treated by Gamma knife from Sept. 1995 to Oct. 1997. Neuroimaging studies performed in 21 patients with more than 12 months showed that tumor size decreased in 9(43%) cases, unchanged in 11(51%) cases, and increased in 1(15%) case. The tumor growth control and regression rates were 95% and 43%, respectively. Some hearing was preserved in four patients(36%) who had hearing piror to Gamma knife treatment. There was new transient facial weakness in five patients(23%), and there was new trigeminal neuropathy after treatment in one patient(4.8%). These findings indicate that Gamma knife therapy is a safe and effective management for acoustic neurinomas, especially in preventing facial function and hearing.

关 键 词：神经瘤.听 立体定向放射外科 治疗 面神经 听神经 听觉障碍 放射效应 副作用 

分 类 号：R739.410.5[医药卫生—肿瘤]