Stable Send-ketals of 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-2'-Ketouridine  

作　　者：Guo Chen CHI Zhong Biao ZHANG Xiao Hua Xu and Ru Yu CHEN (Insitute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry,Nankai University, Tianjin, 300071) 

出　　处：《Chinese Chemical Letters》1998年第11期989-992,共4页中国化学快报（英文版）

摘　　要：A series of stable semi-ketals were obtained via the reactions of 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-ketouridine 1 with primary alcohols. In the addition reaction,only a single diastereomer was observed. The configuration of 3b was confirmed by X-raydiffraction.A series of stable semi-ketals were obtained via the reactions of 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2'-ketouridine 1 with primary alcohols. In the addition reaction,only a single diastereomer was observed. The configuration of 3b was confirmed by X-raydiffraction.

关 键 词：NUCLEOSIDE ketonucleoside semi-ketal configuration 

分 类 号：O621[理学—有机化学]