Structure of neurofilaments studied with scanning tunneling microscopy  

作　　者：Jie Liu Xiangjun Tong Shijin Pang Zhonghe Zhai 

机构地区：[1]Beijing Univ, Coll Life Sci, Beijing 100871, Peoples R China [2]Chinese Acad Sci, Inst Phys, Ctr Condensed Matter Phys, Beijing Lab Vacuum Phys, Beijing 100080, Peoples R China

出　　处：《Chinese Science Bulletin》1998年第21期1805-1809,共5页

摘　　要：Neurofilaments (NFs) were isolated from bovine spinal cord. The structure of purified NFs was studied by scanning tunneling microscopy (STM). The STM images showed that NF was composed of a long core filament and numerous sidearms flanking the rod regularly. The diameter of the rod was about 10 nm (10.2±0.8 nm). Most of the sidearms were short and the distance between two adjacent sidearms was approximately 10 nm. There were some long sidearms between two proximal core filaments. The distance between two adjacent long sidearms was 21 nm. A three-quarter-staggered fashion of native NF structure was put forward.Neurofilaments (NFs) were isolated from bovine spinal cord. The structure of purified NFs was studied by scanning tunneling microscopy (STM). The STM images showed that NF was composed of a long core filament and numerous sidearms flanking the rod regularly. The diameter of the rod was about 10 nm (10.2 ± 0.8 nm). Most of the sidearms were short and the distance between two adjacent sidearms was approximately 10 nm. There were some long sidearms between two proximal core filaments. The distance between two adjacent long sidearms was 21 nm. A three-quarter-staggered fashion of native NF structure was put forward.

关 键 词：NEUROFILAMENT INTERMEDIATE FILAMENT scanning TUNNELING microscopy. 

分 类 号：O488[理学—固体物理]