抑郁症过氧化脂质及谷胱甘肽过氧化物酶研究  

Study of Lipid Peroxide and Glutution Peroxidase in Patients with Depression

作　　者：陈佐明[1] 张建宏[1] 张秀明[1] 

机构地区：[1]河南省精神病医院,453002

出　　处：《中国民康医学》1997年第5期279-280,321,共3页Medical Journal of Chinese People’s Health

摘　　要：３２例抑郁症过氧化脂质及谷胱甘肽过氧化酶水平与正常人（３３人）对照，并对抑郁症Ｌｐｏ与ＨＡＭＤ分值进行相关性分析，结果抑郁症Ｌｐｏ明显高于对照组，且Ｌｐｏ水平与ＨＡＭＤ分值呈正相关。提示：Ｌｐｏ过多可能造成脑细胞脂质过氧化损害而致抑郁。The levels of Lpo and glutution peroxidase were detected respectively in 32 cases of depression and 33 normal controls. The correlation analgsis was taken between the levels of Lpo and grading of HAMD. The results showed that the levels of Lpo were significantly higher in the depressive patients than those in the controls,and there was also positive correlation between Lpo levels and HAMD gradings. It suggests excoessive Lpo may cause cerebrocellular injury and result in depression.

关 键 词：抑郁症 过氧化脂质 

分 类 号：R749.4[医药卫生—神经病学与精神病学]