实验性脑出血后脑血流量变化因素的研究  

EXPERIMENTAL INTRACEREBRAL HEMORRHAGE:EFFECT ON REGIONAL CEREBRAL BLOOD FLOW

作　　者：包仕尧[1] 汤继宏[1] 刘春风[1] 张志琳[1] 赵合庆[1] 

机构地区：[1]苏州医学院种经科学研究所,苏州215004

出　　处：《实用临床医药杂志》1997年第4期238-240,共3页Journal of Clinical Medicine in Practice

摘　　要：作者利用新鲜未肝素化白体血注入大鼠尾状核建立的脑出血模型．观察了实验性脑出血后24小时内不同血肿量和不同出血都位对局部脑血流量（rCBF）变化。结果提示：出血量越大，继发性脑缺血范围越广，持续时间也越长．丘脑出血比尾状核出血所致的远隔区域额叶皮层rCBF下降程度大。Experimental intracerehral hemorrage: Effect on regional cerehra blood flow- By usingthe Tnodel of expcrimerrltal lCH injected fresh nonheparinized autologous arterial blood intothe caudate nucleus of the rat, and hy hydrogen c1earance method to measurs regional cerebral hlood flow (rCBF), Weinvestigated the changes of rCBF in caudate nucleus, thalamus and frontal cortex with in 24 hours of experimental hemorrhage. ln this research we could come to the conclusion that: There was a trend showing anincrease in the area and duration of ischemia with higher injection volumes. The degree of rCBF reductionin the remote frontal lobe distant from the area around the hematoma was more evident in thalamic than incaudate hemorrhage.

关 键 词：大鼠 脑血流量 尾状核出血 丘脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]