补充维生素A对儿童患病的影响  

A study on the impact of large dose of vitamin A supplementation on child morbidity

作　　者：程列[1] 常莹[1] 李丹[1] 贾凤梅[1] 于文涛[1] 王恩霖[1] 焦荣华[1] 李银生[1] 周晓仕 

机构地区：[1]中国预防医学科学院营养与食品卫生研究所,河北省保定地区卫生防疫站,河北省涞源县卫生防疫站

出　　处：《卫生研究》1996年第S1期133-136,共4页Journal of Hygiene Research

摘　　要：作者在前一个实验工作的基础上进一步扩大样本，对６７０名４岁以下儿童进行了为期二年的补充大剂量ＶＡ的实验观察，用双盲法对实验组儿童每６个月补充２０×１０４ＩＵＶＡ，由乡村医生每周访问儿童家长，记录儿童患病情况。结果表明对亚临床ＶＡ缺乏地区儿童补充大剂量ＶＡ能降低腹泻发生率，且其效果在疾病高发月份更明显，结果还表明血清ＶＡ低的儿童补充ＶＡ比血清ＶＡ水平较高的儿童效果明显；但对呼吸道感染性疾病虽然在疾病高发月份实验组发病比对照组低，但总的差异不明显。作者还对疾病资料收集方法进行了讨论。Based on the previous study on the impact of large dose of VA supplementation on child morbidity, the investigators studied it again with larger sample size(670 under 4 year children) and in longer period(2 years).By double blinded method, 20 × 104 IU VA and placebo were given to the studied groups every 6 months, and incidence of diarrhea and respiratory disease was recorded by the village doctors by home visit every week. The results showed that the large dose VA supplementation lowered the incidence of diarrhea of children, especially during the high prevalence season, and the effect was more significant in child with lower serum VA than that with higher serum VA level. Although the incidence of respiratory diseases in study group was lower than that in the control, there were no significant difference between the 2 groups.

关 键 词：维生素A 腹泻 呼吸道感染 儿童 

分 类 号：R151.42[医药卫生—营养与食品卫生学]