化疗对卵巢癌腹膜后淋巴结转移的疗效观察  

Observation on Chemotherapy Effect of Ovarian Cancer Metastasized to Retroperitioneal Lymphnodes

作　　者：唐美琴[1] 张志毅[1] 涂小予[1] 

机构地区：[1]上海医科大学附属肿瘤医院,上海200032

出　　处：《肿瘤学杂志》1995年第4期228-229,共2页Journal of Chinese Oncology

摘　　要：自1986年6月至1993年12月．32例卵巢癌行二探术并作了腹膜后淋巴结清除术．其中上皮性癌20例（62.5％）、生殖细胞瘤12例（37.5％）。Ⅰ期15例，Ⅱ期5剂，Ⅲ期11例，Ⅳ期1例。32例腹膜后淋巴结有转移的9例28.1％,其中上皮性癌淋巴结转移为30.3％（6／20）．生殖细胞瘤淋巴结转移为25.0％（3／12）．Ⅰ期15例均无淋巴结转移．Ⅱ期5例．淋巴结转移40％（2／5）．Ⅲ11例，淋巴结转移54．5％（6／11），Ⅳ期1例有淋巴结转移。本文复查9例腹膜后转移淋巴结的病理．从形态学所见该9例对化疗均无变化。32例二探术中有盆、腹腔残癌者13例（40.6％）．本文对卵巢癌腹膜后转移淋巴结对化疗敏感性问题以及二探术的指证进行了讨论．并提出了的意见。From. June 1986 to December 1993.32 patients with ovarian cancer underwent second-look laparotomy(SLL) and retroperitoneal lymphadenectomy. There were 20 epithelial carcinomas(62.5％)and 12 germ cell tumors (37.5％)The stage distribution was as following: 15 cases were in stage 1.5 cases were in stage Ⅱ,11 cases were in stage Ⅲane 1 case was in stage Ⅳ,The positive retroperitoneal lymph nodes were found in 9 cases (28.1％),The incidences of !lymphatic metastasis were 30.0％(6/20) in epithelial carcinoma and 25. 0％ (3 /12) in germ cell tumor. All 15 cases in stage Ⅰ weren't found to have lymph node metastasis. The incidences of Lymphatic metastasis in 5 case of stage Ⅱ, 11 cases of stage Ⅲ and Ⅰcase of stage Ⅳ were 40％(2/5).51.5％(6/11)and 100％ (1/1) respectively. All nine cases with Positive lymph nodes received chemouherapy befor SLL, but morphologic changes of these tumor cells in lymph nodes were not found affter chemotherapy. Thirteen cases had residual tumors in peritoneal and /or pelvic eavity at SLL.Whether the tumor cells in retroperitoneal lymph node were sensitive to chenotherapy and what is the indieation of SLL are discussed in this paper.

关 键 词：卵巢癌 二探术 腹膜后淋巴结 化疗 

分 类 号：R737.31[医药卫生—肿瘤]