A novel synthetic use of 2-bromo- 1-methylpyridinium iodide for macrolactamization  

作　　者：BAI, Dong-Lu BO, Yun-Xin ZHOU, Qi-Ting Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China 

出　　处：《Chinese Journal of Chemistry》1994年第2期158-168,共11页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China.

摘　　要： Using 2-bromo-1-methylpyridimium iodide as carboxyl activating agent, 10 ansa-macrolactams were prepared conveniently from the corresponding seco-precursor w-aminoacids in the yields of 78-2%.Using 2-bromo-1-methylpyridimium iodide as carboxyl activating agent, 10 ansa-macrolactams were prepared conveniently from the corresponding seco-precursor w-aminoacids in the yields of 78-2%.

关 键 词：LACTAM ansa-macrolactam CYCLIZATION lactamization. 

分 类 号：O621[理学—有机化学]