多系统萎缩  

Multiple System Atrophy

作　　者：王国瑾[1] 柳亚琛[1] 

机构地区：[1]湖北医科大学附属第一医院神经科

出　　处：《卒中与神经疾病》1994年第3期133-136,共4页Stroke and Nervous Diseases

摘　　要：多系统萎缩是一个与Ｓｈｙ－Ｄｒａｇｅｒ综合征、橄榄桥脑小脑萎缩和纹状体黑质变性相重叠的综合征，临床表现包括帕金森综合征、小脑征、锥体束征和植物神经功能损害。本文回顾性分析了六例多系统损害病例，其中四例在临床上可以诊断为多系统萎缩，另二例则需追踪观察和／或高场强ＭＲＩＴ２加权象才能确诊。本文对多系统萎缩的临床表现、病理改变、神经放射学特征、诊断和鉴别诊断进行了讨论。Multipl system atrophy is a syndrome with features overlapping with Shy-Drager syndrome, striatonigral degeneration and olivopotocerebellar atrophy. It is characterized clinically by the combination of parkinsonian,pyramidal,cerebellar and autonomic symptoms. Six cases with a primary diagnosis of multiple system lesions were reviewed retrospectively. The clinical diagnosis of multiple system atrophy could be made with certainty in four cases and in the other two cases further observations and/or high field strength MRl should be needed.The clinical manifestations,the pathological and neuroradiological features,the diagnosis and the differential diagnosis of multiple system atrophy were diacussed.

关 键 词：多系统萎缩 帕金森综合征 橄榄桥脑小脑萎缩 SHY-DRAGER 综合征 纹状体黑质变性 

分 类 号：R741.02[医药卫生—神经病学与精神病学]