直肠癌C_3期的术后放疗  

POSTOPERATIVE IRRADIATION THERAPY IN STAGE C3 ADENOCARCINOMA OF RECTUM

作　　者：刘瑛[1] 朱龙祥 吴根娣 何少琴 莫善兢 

机构地区：[1]上海医科大学肿瘤医院放疗科,200032

出　　处：《中华放射肿瘤学杂志》1993年第4期42-43,82,共3页Chinese Journal of Radiation Oncology

摘　　要：我们收集了1984年1月～1988年12月于我院手术的C_3期直肠癌病人共91例。单纯手术56例,术后加放疗35例,随访率97.8％,综合治疗2例失访,按死亡计算。 术后放疗系手术后半年内放疗,D_T40～45Gy/4～5周,或缩野后追加10～20Gy/1～2.5周。其2年局部复发率,术后放疗组34.3％(12/35例),局部复发加远处转移为42.85％(15/35例),低于单纯手术组局部复发率73％(41/56例),局部复发加远处转移87.5％(49/56例),经统计学处理,复发率X^2=3.81,P=0.06。复发加转移P<0.05,术后放疗组能降低局部复发率。From January 1984 to December 1988, 91 cases of Stage C3 adenpcarcinoma of of rectum were treated. 56 cases received surgery only, 35 cases received surgery in combination with postoperative radiation therapy. Follow up rate was 97- 8%. As literature reports, recurrence rate of Stage C3 rectal cancers was 100% after surgery, 80% of them occurned within 2 years and, 5-year survival rate was zero. Radiotherapy regimen in this study was 40-50 Gy/4-5 weeks to the pelvic, followed by conedown 10-20 Gy/1-2 weeks. Our data showed that postoperative irradiation decreased significantly both recurrence rates (34. 3%, 12/35) and recurrence plus distant metas-tases rates (42. 85%, 15/35), while in surgery alone, it was 73% (41/56) and 87- 5% (49/56) respectively. No severe complication after combination treatment was observed.

关 键 词：直肠肿瘤 放射治疗 手术 

分 类 号：R73[医药卫生—肿瘤]