抗结核散对实验性脾虚小鼠肠道正常菌群及免疫机能影响  

The Influence of the Anti—Tuberculose pulvis on the Normal Intestinal Flora and Immunological Function in Mouse

作　　者：杨景云[1] 李丽秋[1] 陈志[1] 马淑霞[1] 迟振富[1] 张桂春[1] 马里奇 

机构地区：[1]佳木斯医学院微生态学研究室,佳木斯154002 [2]哈尔滨市中山中医慢性病研究所,哈尔滨150036

出　　处：《中国微生态学杂志》1991年第2期11-15,共5页Chinese Journal of Microecology

摘　　要：中药合剂抗结核散在临床上具有抗结核作用,总疗效率达92％,但在试管内未发现有抗结核菌作用。为了探索抗结核散的作用机制,本文特检测该制剂对实验小鼠肠道正常菌群及免疫功能的影响。检测结果证明,抗结核散具有调整肠道菌群和改善免疫功能的作用。因此,本文认为抗结核散的作用机制可能与调整肠菌群和改善免疫功能有关。The Anti—Tuberculosi Pulvis was Preperated from Ma Lichi, a noted traditional physician of China, with Chinese Medicinal Herbs. This drug is of therapeutic efficienee for Tuberculosis, specially, cavenous Qulmanary Tuberculosis. The total cure rate was more than 92%. But it have not any influence for Bacillus tubercule in vitro. In oder to searching the action mechanism of Anti—tuberculose Pulvis, thisspaper was conducted to investigation of normal intestinal flora and Immunological ruction in mous as a 'Pie Xu' model from view point of Chinese traditional medicine resembles the human tuberculosis. The results was shown that the Anti—tuberculsis Pulois could readjust the intestinal flora and the Immunological function from abnormal to noumal. This paper, therefore, considered that the mechanism of Anti—tuberculose Pulvis is associated with the intestinal flora and could improve the host statement.

关 键 词：抗结核散 正常菌群 免疫功能 

分 类 号：Q[生物学] R[医药卫生]