正常妊娠各期桡、尺骨骨矿含量、钙、磷及25(OH)D_3水平的研究  

STUDY ON BONE MINERAL CONTENT,METABOLISM OF CALCIUM AND PHOSPHORUS AND LEVEL OF 25(OH)D_3 IN DIFFERENT MONTHS OF NORMAL PREGNANCY

作　　者：邢淑敏[1] 刘忠厚[1] 蔡淑进 刘广大[1] 刘惠敏[1] 胡明[1] 

机构地区：[1]中日友好医院妇产科临床医学研究所同位素室

出　　处：《中日友好医院学报》1991年第3期145-148,共4页Journal of China-Japan Friendship Hospital

摘　　要：本文测定了1987年9月～1989年9月我院产科门诊未曾服用钙剂及维生素 D,也无代谢性疾病或肾脏病的健康未产妇110人共113次,不同孕月的桡、尺骨骨矿含量,血钙、磷及25(OH)D_3和 AKP 的水平;尿钙及磷的排泄率。发现自第4孕月始骨矿面密度值、血钙水平及尿钙排泄率均有下降趋势;血磷水平有所下降,而尿磷排泄率增高;AKP随孕月有明显增高;25(OH)维生素 D_3处于正常范围。补充钙剂与维生素 D 可以阻断各项指标的变化。本文讨论了各项指标变化的意义并提出了预防措施。Several indices including bone mineral content of radius and ulna (BMC and BMC/BW ),levels of serum calcium (Ca),phosphorus (P),alkaline phosphatase (AKP),25 (OH)D_3and urinary excretion rate of calcium (U-Ca/Cr) and phosphorus (U-P/Cr) were studied in 110healthy pregnant women without either metabolic or renal diseases.All subjects had not takencalcium and vit.D during the period from Sept.1987 to Sept.1989.BMC/BW,calcium levelsand U-Ca/Cr declined from the 4th pregnant month and maintained at the lower limit till fullterm.Levels of phosphorus also declined but U-P/Cr increased.AKP showed apparent increase,and levels of 25(OH)D_3 remained at normal range.Administration of calcium and Vit.D couldblock all changes mentioned above.The significance of the changes of these indices were discussedand the preventive measures proposed.

关 键 词：妊娠期 骨矿含量 钙、磷代谢 25(OH)D₃ 

分 类 号：R[医药卫生]