麻黄碱衍生物的合成  

THE SYNTHESIS OF EPHEDRINE DERIVATIVES

作　　者：程石泉[1] 高远洪[1] 庞素华[2] 牛向荣 杨慧[1] 

机构地区：[1]内蒙古医学院有机化学教研室 [2]内蒙古医学院药学系

出　　处：《内蒙古医科大学学报》1990年第1期38-40,54,共4页Journal of Inner Mongolia Medical University

摘　　要：本文报道1-{2-[3-苯基-3-羟基-2-丙基甲胺基]乙基}-(3)-吡啶基酮(Ⅰ_(a-b)),1-3-{2-[3-苯基-3-羟基-2-丙基甲胺基]亚甲基}吲嗓(Ⅱ)和二个羧酸甲基麻黄碱酯(Ⅲ_(a-b)),共五种新化合物。1-{2-[3-Phenyl-3-hydroxy-propyl-(2)-methylamino] ethyl} pyridyl-(3)-ketone(Ⅰ_(a-b)), 1-3{2-[3-phenyl-3- hydroxy-propyl-(2)-methylamino] methylene} indole (Ⅱ_a) and two Methyl-ephedrine carbocylic acid esters (Ⅲ_(a-b)) were synthesized, which possess some biological activity.The structures of all the compounds synthesized were confirmed by elementary analysis and IR spectra.

关 键 词：曼尼希碱 吲哚 3-乙酰基吡啶 羧酸甲基麻黄碱酯 

分 类 号：R[医药卫生]