THE ANTITUMOR ACTIVITY OF LYMPHOTOXIN AND THE EFFECT OF INTERLEUKIN-2 ON ITS FUNCTION  

作　　者：沈泽荔 何俊森 

机构地区：[1]The Department of Microbiology, Henan Medical University, Zhengzhou

出　　处：《Chinese Journal of Cancer Research》1990年第4期45-49,共5页中国癌症研究（英文版）

摘　　要：The effect of lymphotoxin (LT)-containing supernatant produced by lectin-stimulated human lymphocytes on tumor cells and the relation between interleukin-2 (IL-2) and LT were studied in this article. Results showed that LT-containing superna-tants had cytotoxicities on many different kinds of tumor cells from human and mice, that actinomycin D increased the LT activities on target cells and that IL-2 had the ability to increase the cytotoxicity of human PBMC on tumor cells, after being treated with LT, the target cells were more easy to kill by PBMC as well.The effect of lymphotoxin (LT)-containing supernatant produced by lectin-stimulated human lymphocytes on tumor cells and the relation between interleukin-2 (IL-2) and LT were studied in this article. Results showed that LT-containing superna-tants had cytotoxicities on many different kinds of tumor cells from human and mice, that actinomycin D increased the LT activities on target cells and that IL-2 had the ability to increase the cytotoxicity of human PBMC on tumor cells, after being treated with LT, the target cells were more easy to kill by PBMC as well.

关 键 词：THE ANTITUMOR ACTIVITY OF LYMPHOTOXIN AND THE EFFECT OF INTERLEUKIN-2 ON ITS FUNCTION MTT 

分 类 号：R73[医药卫生—肿瘤]