直肠癌术前放疗的疗效观察  

PREOPERATIVE RADIOTHERAPY FOR RECTAL CANCER

作　　者：王宝连[1] 许秀峰[1] 阴慎齐 贾益友 毕学玉 张淑芬[1] 胡庚坤[1] 富鹰[1] 杨春生[1] 

机构地区：[1]河北省职工医学院附属医院

出　　处：《中华放射肿瘤学杂志》1990年第2期4-6,共3页Chinese Journal of Radiation Oncology

摘　　要：直肠癌首选手术治疗历时八十余年,其远期疗效无明显提高。近些年来,国内外一些学者主张直肠癌采用综合治疗,术前放疗遂被采用。我科治疗的部分直肠癌病例采用术前放疗组与单纯手术组对照,结果表明,术前放疔可提高疗效,现报道如下。This paper reports 88 cases of rectal cancer treated from 1979 to 1984, propectively randomized into preoperative radiotherapy (PR group - 44 cases) and surgery only (OP group 44 cases) . In the PR group, all were irradiated by betatron (22 MV-X ray) or telecobalt through 2 fields set from L4 to anus encompassing the margins of true pelvis. The dose used was 3112-4000 cGy/3-4 wks. The patients had a rest of 10-14 dsys before operation. After the radiotherapy, symptomatic improvement was 76-90%. tumor reduction was 52%. Difficulty in operation was not increased. In PR group and OP group,the rates of radical resection were 77% (34/44) and 57% (25/44) ,5 year survival rates after radical resection were 62% (21/34) and 36% (9/25) , the incidence of the local recurrence were 12% (4/34) and 36% (9/25) , respectively. It is suggested that preoperative radiotherapy for rectal cancer improve the rate of radical resection, 5 year survival and reduce the recurrence. Preoperative radiotherapy is valuable in the combination therapy for rectal cancer.

关 键 词：术前放疗 单纯手术组 远期疗效 区域淋巴结转移 手木 局部复发率 骨盆缘 亚临床 直肠痛 黑色素瘤 

分 类 号：R73[医药卫生—肿瘤]