猫海马微量注射去甲肾上腺素对血浆皮质醇浓度的影响  

EFFECT OF MICROINJECTION OF NOREPINEPHRINE INTO THE HIPPOCAMPUS ON PLASMA CORTISOL CONCENTRATION IN CATS

作　　者：朱晓蔓[1] 朱子涛[1] 陈彤[2] 高杨 周予谦[1] 

机构地区：[1]南京铁道医学院生理学教研室 [2]南京大学生物系生理专业

出　　处：《东南大学学报（医学版）》1990年第3期137-140,143,共5页Journal of Southeast University(Medical Science Edition)

摘　　要：作者观察了乌拉坦—氯醛糖麻醉的猫,海马不同区域微量注射去甲肾上腺素(NE)对血浆皮质醇浓度的影响。结果表明,在腹侧海马(VHPC)组,NE使血浆皮质醇浓度升高到注药前对照值的72±15％,与生理盐水对照组相比有非常显著的差异(P<0.01)。但是,在背侧海马(DHPC)组,NE使血浆皮质醇浓度升高到注药前对照值的15±13％,与生理盐水组相比无显著差异(P>0.05)。结果提示,腹侧海马NE递质可能参与了垂体—肾上腺皮质功能的中枢调控机制。The results of our experiments showed that in the ventral hippoeampus (VHPC) group, the plasma eortisol concentration was incieased by 72±15% ( X±SX) after microinjection of norepinephrine (NE), which is very significantly higher than that of normal saline group ( P<0.01 ); in the dorsal hippocampus (DHPC) group, it was decreased bY. 15±13% and no significant difference between the DHPC and normal saline group (P>0.05) was found. The results suggest that the NE system in the VHPC is involved in central neuial control of pituitary adrenal function,

关 键 词：去甲肾上腺素 海马 肾上腺皮质激素类 猫 

分 类 号：R[医药卫生]