右室相关心律失常的临床和基础  

Progress in Investigations of Arrhythmias Originating in the Right Ventricle

作　　者：胡金柱[1] 洪葵[1] 

机构地区：[1]南昌大学第二附属医院心内科,江西南昌330006

出　　处：《心血管病学进展》2011年第6期883-887,共5页Advances in Cardiovascular Diseases

摘　　要：冠心病或心肌病所致左室结构和电重构是室性心律失常和心源性猝死发生的主要原因。近20年来,右室相关心律失常已受到工作者重视,其好发于青壮年患者,易导致心源性猝死,基础研究尤其是分子遗传学的发展推动了人们对右室相关心律失常发病机制、诊断和预后的认识和理解。右室相关心律失常多见于致心律失常型右室心肌病、Brugada综合征、右室流出道室性心动过速及先天性心脏病等,现将对其临床与基础研究进行概述。The structural and electrical remodeling in the left ventricle as a result of coronary heart disease and cardiomyopathy is the primary cause of ventricular arrhythmia and sudden cardiac death.However,arrhythmias can also originate in the right ventricle.Ventricular arrhythmias originating in the right ventricle usually affect younger patients,and can also lead to sudden cardiac death.Advances in available research techniques are providing more information about the pathogenesis,diagnosis and prognosis of right ventricular arrhythmias.Arrhythmias originating in the right ventricle mostly occur in arrhythmogenic right ventricular cardiomyopathy/dysplasia,Brugada syndrome,right ventricular outflow tract ventricular tachycardia,and congenital heart defects.This article reviews recent research in these diseases and their connection to right ventricular arrhythmias.

关 键 词：致心律失常型右室心肌病 BRUGADA综合征 右室流出道室性心动过速 先天性心脏病 心源性猝死 

分 类 号：R541.7[医药卫生—心血管疾病]