慢性肝炎患者生命质量测定量表研制与考评  

Development and Evaluation of Quality of Life Instruments for Chronic Diseases-Chronic Hepatitis

作　　者：王超秀[1] 万崇华[2] 李武[3] 李晓梅[4] 许传志[4] 张晓磬[4] 

机构地区：[1]内江市第一人民医院感染科,四川省内江市641000 [2]广东医学院人文与管理学院暨生命质量与应用心理研究中心 [3]昆明医学院第一附属医院传染科 [4]昆明医学院公共卫生学院卫生统计教研室

出　　处：《中国全科医学》2011年第31期3562-3565,共4页Chinese General Practice

基　　金：国家自然科学基金(30360092;30860248)

摘　　要：目的研制和评价慢性病患者生命质量测定量表体系中的慢性肝炎量表(QLICD-CH)。方法结合中国文化背景进行量表(QLICD-CH)研制,并用此量表调查108例慢性肝炎住院患者,对QLICD-CH的信度、效度和反应度进行评价。结果该量表各个领域克朗巴赫系数(Cronbach'sα)均>0.7,分半信度系数多数>0.6,重测相关系数均>0.9。共性模块提取9个公因子,特异模块提取4个公因子,涵盖大部分条目信息。以汉化版的医学结局调查表(SF-36)各个领域得分作为效标,QLICD-CH各个领域及量表总分与SF-36相应效标的相关程度较好。QLICD-CH第一次和第三次测定得分进行比较,除了心理功能领域、社会功能领域外,其他领域得分治疗前后比较,差异均有统计学意义(P<0.01)。结论 QLICD-CH具有较好的信度、效度、反应度,可作为中国慢性肝炎患者的生命质量测评工具。Objective To develop and evaluate the quality of life instruments for chronic diseases-chronic hepatitis（QLICD-CH）. Methods The scale was developed in accordance with Chinese culture background and assessed by analyzing data from 108 inpatients in the aspects of validity,reliability and responsiveness. Results Cronbach＇s Alpha of each domain exceeded 0.7,the split-half was also above 0.6,test-retest reliability of the scale,as assessed with the correlation coefficient was above 0.9;nine principle components were extracted from the general module of instrument,four principle components were extracted from the specific module,which reflected contents of most items.The correlations between coefficients of each domain as well as total score of QLICD-CH and SF-36 were fairly high.Except from psychological domain,social domain,scores of the other domains showed statistically significant differences before and after treatment（P0.01）. Conclusion The QLICD-CH has good validity,reliability and responsiveness and can be used in the quality of life assessment of patients with chronic hepatitis.

关 键 词：肝炎 慢性 生命质量 信度 效度 反应度 

分 类 号：R575.1[医药卫生—消化系统]