基于B样条的弹性配准在放疗CT图像间配准的应用  

CT Images Non-rigid Registration Using the B Spline in Radiotherapy

作　　者：庞皓文[1] 孙小扬[1] 杨波[1] 罗惠群[1] 吴虹[1] 吴敬波[1] 

机构地区：[1]泸州医学院附属医院肿瘤科,四川泸州646000

出　　处：《中国医学物理学杂志》2011年第5期2887-2889,共3页Chinese Journal of Medical Physics

摘　　要：目的:应用B样条弹性模型研究肿瘤患者放疗前CT图像与放疗后CT图像之间的弹性配准。方法:利用B样条自由弹性模型(free-form deformations,FFD),以灰度差平方和(Sum of Squared Differences,SSD)为相似性测度函数,通过基于多分辨率的B样条弹性配准方法对同一患者放疗前与放疗后的CT图像进行配准。结果:图像通过高斯滤波处理,应用B样条弹性模型,得到较为理想的弹性配准实验结果。结论:基于B样条的CT与CT图像弹性配准可以较好地建模放疗前与放疗后肿瘤区域的形变,为临床分析肿瘤的变化提供支持。Objective： To investigate CT image non-rigid registration using the B spline in Radiotherapy.Methods： Using B-spline free-form deformations model and SSD as a similarity measure function,based on multi-resolution B-spline non-rigid registration method to registration CT image with the same patient before and after radiotherapy.Results： The non-rigid registration result is more satisfactory by Gaussian filtering image and using B-spline free-form deformations model. Conclusions： CT image non-rigid registration using the B spline can be modeling deformation of the tumor region,and provide support for clinical analysis of changes in the tumor.

关 键 词：B样条 弹性配准 自由形变模型 CT 

分 类 号：R811.1[医药卫生—放射医学]